Total mesorectal excision: What are we doing?

David B. Stewart, David W. Dietz

Research output: Contribution to journalReview articlepeer-review

32 Scopus citations


The introduction of total mesorectal excision (TME) for rectal cancer has reduced local recurrence rates and improved oncologic outcomes, although complication rates such as anastomotic leak have also been a consequence. With the advent of neoadjuvant therapy for rectal cancer, many are questioning how this development may change the role of TME. This review presents a history of how TME evolved and a description of this technique. Complication rates, the impact of neoadjuvant therapy on local recurrence, variations of TME such as nerve-sparing proctectomy and cancer-specific mesorectal excision, and a review of functional outcomes for various methods of reconstruction are presented.

Original languageEnglish (US)
Pages (from-to)190-202
Number of pages13
JournalClinics in Colon and Rectal Surgery
Issue number3
StatePublished - Aug 2007

All Science Journal Classification (ASJC) codes

  • Surgery
  • Gastroenterology


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