Total parenteral nutrition via multilumen catheters does not increase the risk of catheter-related sepsis: A randomized, prospective study

Thomas Y. Ma, Rody Yoshinaka, Alicia Banaag, Beverly Johnson, Sandra Davis, Stephen M. Berman

Research output: Contribution to journalArticle

44 Scopus citations

Abstract

The purpose of this study was to determine in a randomized, prospective manner whether administration of total parenteral nutrition (TPN) via multilumen catheters increases the risk of catheter-related sepsis (CRS). All patients receiving hyperalimentation during a 24-month period were randomized to receive either a double-lumen catheter (DLC) or a triple-lumen catheter (TLC). A total of 101 catheters were placed in 79 patients, of which 49 were DLCs and 52 were TLCs. The patients with DLCs received a total of 784 days of TPN, whereas patients with TLCs received a total of 754 days of TPN. CRS was associated with one (2.0%) of the 49 DLCs vs. one (1.9%) of the 52 TLCs. In comparison, the rate of CRS associated with single-lumen catheters (historical control) at our institution was 1.4% (P > .90). We conclude that the use of multilumen catheters in TPN therapy does not result in an increased risk of CRS.

Original languageEnglish (US)
Pages (from-to)500-503
Number of pages4
JournalClinical Infectious Diseases
Volume27
Issue number3
DOIs
StatePublished - Jan 1 1998

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

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