Total synthesis of (±)-γ-lycorane via the electrocyclic ring closure of a divinylpyrroline

Raymond J. Huntley, Raymond L. Funk

Research output: Contribution to journalArticle

17 Scopus citations

Abstract

A concise total synthesis of (±)-γ-lycorane is described. The key step in the synthesis is the 6π-electrocyclic ring closure of a divinylpyrroline to give a tetrahydroindole, which is subsequently hydrogenated to give the all-cis indolizidine core.

Original languageEnglish (US)
Pages (from-to)6671-6674
Number of pages4
JournalTetrahedron Letters
Volume52
Issue number50
DOIs
StatePublished - Dec 14 2011

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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