Total synthesis of celogentin C by stereoselective C-H activation

Yiqing Feng, Gong Chen

Research output: Contribution to journalArticlepeer-review

240 Scopus citations

Abstract

(Figure Presented) A total gent: Inspired by the biosynthesis of celogentin C, a highly stereoselective and efficient palladium-catalyzed C-H functionalization strategy is employed to construct the key Leu-Trp linkage of this bicyclic compound. A streamlined synthesis is completed in 23 steps from simple amino acid building blocks.

Original languageEnglish (US)
Pages (from-to)958-961
Number of pages4
JournalAngewandte Chemie - International Edition
Volume49
Issue number5
DOIs
StatePublished - Jan 25 2010

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)

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