Total synthesis of (±)-communesin F via a cycloaddition with indol-2-one

Johannes Belmar, Raymond L. Funk

Research output: Contribution to journalArticlepeer-review

82 Scopus citations

Abstract

A concise total synthesis of (±)-communesin F has been completed in 15 linear steps from 4-bromotryptophol in an overall yield of 6.7%. A key step features the cycloaddition of indol-2-one with 3-(2-azidoethyl)-4-bromoindole and facilitates the rapid construction of the lower aminal-containing tetracyclic core of the natural product.

Original languageEnglish (US)
Pages (from-to)16941-16943
Number of pages3
JournalJournal of the American Chemical Society
Volume134
Issue number41
DOIs
StatePublished - Oct 17 2012

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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