Total synthesis of the polycyclic fungal metabolite (±)-communesin F

Peng Liu, Jae Hong Seo, Steven M. Weinreb

Research output: Contribution to journalArticlepeer-review

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(Chemical Equation Presented) What the Heck: The heptacyclic fungal alkaloid communesin F was the target of a total synthesis featuring a rare example of an intramolecular Heck cyclization of a tetrasubstituted alkene, a reductive cyclization of an N-Boc aniline, a stereoselective C allylation of a lactam, and an azide reduction/N-Boc-d-lactam ring opening sequence (see scheme, BOM=benzyloxymethyl).

Original languageEnglish (US)
Pages (from-to)2000-2003
Number of pages4
JournalAngewandte Chemie - International Edition
Issue number11
StatePublished - Mar 8 2010

All Science Journal Classification (ASJC) codes

  • Catalysis
  • Chemistry(all)


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