Total synthesis of the sesquiterpene (±)-illudin C via an intramolecular nitrile oxide cycloaddition

Ronald A. Aungst, Collin Chan, Raymond L. Funk

Research output: Contribution to journalArticle

28 Scopus citations

Abstract

(Equation presented) A convergent total synthesis of illudin C is described. The tricyclic ring system of the natural product was quickly assembled from cyclopropane and cyclopentene precursors via a novel oxime dianion coupling reaction and a subsequent intramolecular nitrile oxide-olefin cycloaddition.

Original languageEnglish (US)
Pages (from-to)2611-2613
Number of pages3
JournalOrganic Letters
Volume3
Issue number16
DOIs
StatePublished - Aug 9 2001

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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