There have been several isolated attempts to automate aspects of the construction project delivery process. These have only been marginally successful and it is increasingly being recognized that significant improvements can only be made through an integrated approach that involves the synergistic integration of information technologies into the project delivery process. A cyber-physical systems approach is expected to reduce the tremendous losses that are directly attributable to the inefficiencies associated with the lack of effective integration. This paper describes a specific effort that seeks to facilitate real-time consistency checking between virtual models and the physical construction. It argues for the effective integration of computational resources (such as wireless sensors, virtual prototyping,real-time tracking and data fusion) with the design and construction process, and outlines how bi-directional consistency can be maintained between the virtual models (which are often ignored once the physical construction commences) and the physical facility. The opportunity offered by the adoption of a cyber-physical systems approach to make the construction process more intelligent and sustainable is discussed and the key benefits highlighted.