Towards a Low-Cost and Portable Photoacoustic Microscope for Point-of-Care and Wearable Applications

Ajay Dangi, Sumit Agrawal, Gaurav Ramesh Datta, Visweshwar Srinivasan, Sri Rajasekhar Kothapalli

Research output: Contribution to journalArticlepeer-review

4 Scopus citations

Abstract

Several breakthrough applications in biomedical imaging have been reported in the recent years using advanced photoacoustic microscopy imaging systems. While two-photon and other optical microscopy systems have recently emerged in portable and wearable form, there is much less work reported on the portable and wearable photoacoustic microscopy (PAM) systems. Working towards this goal, we report our studies on a low-cost and portable photoacoustic microscopy system that uses a custom fabricated 2.5 mm diameter ring ultrasound transducer integrated with a fiber-coupled laser diode. The ultrasound transducer is centered at 17.25 MHz, and shows 45% and 100% fractional bandwidths for ultrasound pulse-echo and photoacoustic A-line signals respectively. To achieve overall system portability, besides the imaging head, other back-end imaging system components need to be readily portable as well. In this direction, we have studied the potential use of compact pre-amplifiers, scanning stages and microcontroller-based data acquisition and reconstruction for photoacoustic imaging. The portable PAM system is validated by imaging phantoms embedded with light absorbing targets. Future directions that will likely help achieve a completely portable and wearable photoacoustic microscopy system are discussed.

Original languageEnglish (US)
Article number8801865
Pages (from-to)6881-6888
Number of pages8
JournalIEEE Sensors Journal
Volume20
Issue number13
DOIs
StatePublished - Jul 1 2020

All Science Journal Classification (ASJC) codes

  • Instrumentation
  • Electrical and Electronic Engineering

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