Towards a micromechanical model of intervertebral disc degeneration under cyclic loading

Anand R. Makwana, A. R. Krishna, Hao Yuan, Reuben H. Kraft, Xianlian Zhou, Andrzei J. Przekwas, Phillip Whitley

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

A number of activities subject the spinal cord [1] to various loading conditions that lead to disc degeneration. In this paper a brief overview on the understanding of the micromechanics and mechanisms of intervertebral disc degeneration is presented and extended to include water loss and disc height change. The focus is on a computational model of the intervertebral disc degeneration that attempts to capture the initiation and the progression of the damage mechanism under fatigue. This model can be used to study the effects on disc under short or long period biomechanical loading in work or combat environments.

Original languageEnglish (US)
Title of host publicationBiomedical and Biotechnology Engineering
PublisherAmerican Society of Mechanical Engineers (ASME)
ISBN (Electronic)9780791846469
DOIs
StatePublished - Jan 1 2014
EventASME 2014 International Mechanical Engineering Congress and Exposition, IMECE 2014 - Montreal, Canada
Duration: Nov 14 2014Nov 20 2014

Publication series

NameASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
Volume3

Other

OtherASME 2014 International Mechanical Engineering Congress and Exposition, IMECE 2014
CountryCanada
CityMontreal
Period11/14/1411/20/14

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All Science Journal Classification (ASJC) codes

  • Mechanical Engineering

Cite this

Makwana, A. R., Krishna, A. R., Yuan, H., Kraft, R. H., Zhou, X., Przekwas, A. J., & Whitley, P. (2014). Towards a micromechanical model of intervertebral disc degeneration under cyclic loading. In Biomedical and Biotechnology Engineering (ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE); Vol. 3). American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/IMECE201439174