Towards very high resolution imaging in ultrasound-modulated optical tomography of biological tissues

Sava Sakadžić; Sri Rajasekhar Kothapalli; Lihong V. Wang

doi:10.1117/12.645285

Towards very high resolution imaging in ultrasound-modulated optical tomography of biological tissues

Sava Sakadžić, Sri Rajasekhar Kothapalli, Lihong V. Wang

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

We explored the possibility of applying very high ultrasound frequencies to achieve very high resolution in ultrasound-modulated optical tomography of soft biological tissues. The ultrasound-modulated coherent light that traversed the scattering biological tissue was detected by a long-cavity and a large etendue confocal Fabry-Perot interferometer. We used various focused ultrasound transducers of 15 MHz, 30 MHz, and 50 MHz to obtain two dimensional images of optically absorbing objects positioned at a few millimeters depth below the surface of both optically scattering phantoms and soft biological tissue samples. This technology is complementary to other imaging technologies, such as confocal microscopy and optical-coherence tomography, and has potential for broad biomedical applications.

Original language	English (US)
Title of host publication	Proceedings of SPIE - The International Society for Optical Engineering
DOIs	https://doi.org/10.1117/12.645285
State	Published - May 9 2006
Event	7th Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics - Photons Plus Ultrasound: Imaging and Sensing 2006 - San Jose, CA, United States Duration: Jan 22 2006 → Jan 26 2006

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	6086
ISSN (Print)	0277-786X

Other

Other	7th Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics - Photons Plus Ultrasound: Imaging and Sensing 2006
Country	United States
City	San Jose, CA
Period	1/22/06 → 1/26/06

All Science Journal Classification (ASJC) codes

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

Access to Document

10.1117/12.645285

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Sakadžić, S., Kothapalli, S. R., & Wang, L. V. (2006). Towards very high resolution imaging in ultrasound-modulated optical tomography of biological tissues. In Proceedings of SPIE - The International Society for Optical Engineering [608614] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 6086). https://doi.org/10.1117/12.645285

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Sakadžić, S, Kothapalli, SR & Wang, LV 2006, Towards very high resolution imaging in ultrasound-modulated optical tomography of biological tissues. in Proceedings of SPIE - The International Society for Optical Engineering., 608614, Proceedings of SPIE - The International Society for Optical Engineering, vol. 6086, 7th Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics - Photons Plus Ultrasound: Imaging and Sensing 2006, San Jose, CA, United States, 1/22/06. https://doi.org/10.1117/12.645285

Towards very high resolution imaging in ultrasound-modulated optical tomography of biological tissues. / Sakadžić, Sava; Kothapalli, Sri Rajasekhar; Wang, Lihong V.

Proceedings of SPIE - The International Society for Optical Engineering. 2006. 608614 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 6086).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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