Towards very high resolution imaging in ultrasound-modulated optical tomography of biological tissues

Sava Sakadžić, Sri Rajasekhar Kothapalli, Lihong V. Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

We explored the possibility of applying very high ultrasound frequencies to achieve very high resolution in ultrasound-modulated optical tomography of soft biological tissues. The ultrasound-modulated coherent light that traversed the scattering biological tissue was detected by a long-cavity and a large etendue confocal Fabry-Perot interferometer. We used various focused ultrasound transducers of 15 MHz, 30 MHz, and 50 MHz to obtain two dimensional images of optically absorbing objects positioned at a few millimeters depth below the surface of both optically scattering phantoms and soft biological tissue samples. This technology is complementary to other imaging technologies, such as confocal microscopy and optical-coherence tomography, and has potential for broad biomedical applications.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
DOIs
StatePublished - May 9 2006
Event7th Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics - Photons Plus Ultrasound: Imaging and Sensing 2006 - San Jose, CA, United States
Duration: Jan 22 2006Jan 26 2006

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume6086
ISSN (Print)0277-786X

Other

Other7th Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics - Photons Plus Ultrasound: Imaging and Sensing 2006
CountryUnited States
CitySan Jose, CA
Period1/22/061/26/06

All Science Journal Classification (ASJC) codes

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    Sakadžić, S., Kothapalli, S. R., & Wang, L. V. (2006). Towards very high resolution imaging in ultrasound-modulated optical tomography of biological tissues. In Proceedings of SPIE - The International Society for Optical Engineering [608614] (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 6086). https://doi.org/10.1117/12.645285