Abstract
We explored the possibility of applying very high ultrasound frequencies to achieve very high resolution in ultrasound-modulated optical tomography of soft biological tissues. The ultrasound-modulated coherent light that traversed the scattering biological tissue was detected by a long-cavity and a large etendue confocal Fabry-Perot interferometer. We used various focused ultrasound transducers of 15 MHz, 30 MHz, and 50 MHz to obtain two dimensional images of optically absorbing objects positioned at a few millimeters depth below the surface of both optically scattering phantoms and soft biological tissue samples. This technology is complementary to other imaging technologies, such as confocal microscopy and optical-coherence tomography, and has potential for broad biomedical applications.
| Original language | English (US) |
|---|---|
| Title of host publication | Proceedings of SPIE - The International Society for Optical Engineering |
| DOIs | |
| State | Published - May 9 2006 |
| Event | 7th Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics - Photons Plus Ultrasound: Imaging and Sensing 2006 - San Jose, CA, United States Duration: Jan 22 2006 → Jan 26 2006 |
Publication series
| Name | Proceedings of SPIE - The International Society for Optical Engineering |
|---|---|
| Volume | 6086 |
| ISSN (Print) | 0277-786X |
Other
| Other | 7th Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics - Photons Plus Ultrasound: Imaging and Sensing 2006 |
|---|---|
| Country | United States |
| City | San Jose, CA |
| Period | 1/22/06 → 1/26/06 |
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All Science Journal Classification (ASJC) codes
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering
Cite this
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Towards very high resolution imaging in ultrasound-modulated optical tomography of biological tissues. / Sakadžić, Sava; Kothapalli, Sri-Rajasekhar; Wang, Lihong V.
Proceedings of SPIE - The International Society for Optical Engineering. 2006. 608614 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 6086).Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
TY - GEN
T1 - Towards very high resolution imaging in ultrasound-modulated optical tomography of biological tissues
AU - Sakadžić, Sava
AU - Kothapalli, Sri-Rajasekhar
AU - Wang, Lihong V.
PY - 2006/5/9
Y1 - 2006/5/9
N2 - We explored the possibility of applying very high ultrasound frequencies to achieve very high resolution in ultrasound-modulated optical tomography of soft biological tissues. The ultrasound-modulated coherent light that traversed the scattering biological tissue was detected by a long-cavity and a large etendue confocal Fabry-Perot interferometer. We used various focused ultrasound transducers of 15 MHz, 30 MHz, and 50 MHz to obtain two dimensional images of optically absorbing objects positioned at a few millimeters depth below the surface of both optically scattering phantoms and soft biological tissue samples. This technology is complementary to other imaging technologies, such as confocal microscopy and optical-coherence tomography, and has potential for broad biomedical applications.
AB - We explored the possibility of applying very high ultrasound frequencies to achieve very high resolution in ultrasound-modulated optical tomography of soft biological tissues. The ultrasound-modulated coherent light that traversed the scattering biological tissue was detected by a long-cavity and a large etendue confocal Fabry-Perot interferometer. We used various focused ultrasound transducers of 15 MHz, 30 MHz, and 50 MHz to obtain two dimensional images of optically absorbing objects positioned at a few millimeters depth below the surface of both optically scattering phantoms and soft biological tissue samples. This technology is complementary to other imaging technologies, such as confocal microscopy and optical-coherence tomography, and has potential for broad biomedical applications.
UR - http://www.scopus.com/inward/record.url?scp=33646246387&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33646246387&partnerID=8YFLogxK
U2 - 10.1117/12.645285
DO - 10.1117/12.645285
M3 - Conference contribution
AN - SCOPUS:33646246387
SN - 0819461288
SN - 9780819461285
T3 - Proceedings of SPIE - The International Society for Optical Engineering
BT - Proceedings of SPIE - The International Society for Optical Engineering
ER -