Abstract
The purpose of this chapter is to selectively review the literature on the neuroanatomical, neuropsychological, and emotional/behavioral effects of exposure to three different substances: organic solvents, lead, and carbon monoxide. Recent research regarding each of these substances has provided a window into the mechanisms for changes in behavior and cognition. There are far too many substances known to affect the central nervous system to review them all here. In addition, the volume of literature on each of the substances we discuss is too large for comprehensive review. Rather, our goal is to provide clinicians with a theoretical background of the changes in behavior/emotions and cognition commonly observed with exposure to these substances and to provide guidance for assessing exposed individuals. For each substance, we will review the particulars of exposure and symptom expression, the neurobehavioral symptoms, the neuroimaging changes, and the relationship between these. Based upon these findings, where possible, we will recommend areas to focus on and hypotheses to explore when evaluating patients with such exposures. We will finish up by addressing general themes for the assessment of patients with a history of toxic exposure, including measurement of exposure, determination of effort in medical-legal cases, and collaboration with occupational medicine specialists.
| Original language | English (US) |
|---|---|
| Title of host publication | Handbook of Medical Neuropsychology |
| Subtitle of host publication | Applications of Cognitive Neuroscience |
| Publisher | Springer New York |
| Pages | 479-489 |
| Number of pages | 11 |
| ISBN (Print) | 9781441913630 |
| DOIs | |
| State | Published - Dec 1 2010 |
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All Science Journal Classification (ASJC) codes
- Psychology(all)
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Toxic disorders and encephalopathy. / Haut, Marc W.; Moran, Maria; Lonser, Kara.
Handbook of Medical Neuropsychology: Applications of Cognitive Neuroscience. Springer New York, 2010. p. 479-489.Research output: Chapter in Book/Report/Conference proceeding › Chapter
TY - CHAP
T1 - Toxic disorders and encephalopathy
AU - Haut, Marc W.
AU - Moran, Maria
AU - Lonser, Kara
PY - 2010/12/1
Y1 - 2010/12/1
N2 - The purpose of this chapter is to selectively review the literature on the neuroanatomical, neuropsychological, and emotional/behavioral effects of exposure to three different substances: organic solvents, lead, and carbon monoxide. Recent research regarding each of these substances has provided a window into the mechanisms for changes in behavior and cognition. There are far too many substances known to affect the central nervous system to review them all here. In addition, the volume of literature on each of the substances we discuss is too large for comprehensive review. Rather, our goal is to provide clinicians with a theoretical background of the changes in behavior/emotions and cognition commonly observed with exposure to these substances and to provide guidance for assessing exposed individuals. For each substance, we will review the particulars of exposure and symptom expression, the neurobehavioral symptoms, the neuroimaging changes, and the relationship between these. Based upon these findings, where possible, we will recommend areas to focus on and hypotheses to explore when evaluating patients with such exposures. We will finish up by addressing general themes for the assessment of patients with a history of toxic exposure, including measurement of exposure, determination of effort in medical-legal cases, and collaboration with occupational medicine specialists.
AB - The purpose of this chapter is to selectively review the literature on the neuroanatomical, neuropsychological, and emotional/behavioral effects of exposure to three different substances: organic solvents, lead, and carbon monoxide. Recent research regarding each of these substances has provided a window into the mechanisms for changes in behavior and cognition. There are far too many substances known to affect the central nervous system to review them all here. In addition, the volume of literature on each of the substances we discuss is too large for comprehensive review. Rather, our goal is to provide clinicians with a theoretical background of the changes in behavior/emotions and cognition commonly observed with exposure to these substances and to provide guidance for assessing exposed individuals. For each substance, we will review the particulars of exposure and symptom expression, the neurobehavioral symptoms, the neuroimaging changes, and the relationship between these. Based upon these findings, where possible, we will recommend areas to focus on and hypotheses to explore when evaluating patients with such exposures. We will finish up by addressing general themes for the assessment of patients with a history of toxic exposure, including measurement of exposure, determination of effort in medical-legal cases, and collaboration with occupational medicine specialists.
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UR - http://www.scopus.com/inward/citedby.url?scp=84889988597&partnerID=8YFLogxK
U2 - 10.1007/978-1-4419-1364-7_26
DO - 10.1007/978-1-4419-1364-7_26
M3 - Chapter
AN - SCOPUS:84889988597
SN - 9781441913630
SP - 479
EP - 489
BT - Handbook of Medical Neuropsychology
PB - Springer New York
ER -