TY - JOUR
T1 - Trait hostility and cortisol sensitivity following a stressor
T2 - The moderating role of stress-induced heart rate variability
AU - Murdock, Kyle W.
AU - LeRoy, Angie S.
AU - Fagundes, Christopher P.
N1 - Funding Information:
The data used for this article were collected by the Laboratory for the Study of Stress, Immunity, and Disease at Carnegie Mellon University under the directorship of Sheldon Cohen, PhD; and were accessed via the Common Cold Project (CCP) website ( www.commoncoldproject.com ). CCP data are made publically available through a grant from the National Center for Complementary and Integrative Health ( AT006694 ); the conduct of the study was supported by a grant from the National Institute of Allergy and Infectious Diseases ( R01 AI066367 ); secondary support was provided by a grant from the National Institutes of Health to the University of Pittsburgh Clinical and Translational Science Institute ( UL1 RR024153 ); and supplemental support was provided by John D. and Catherine T. MacArthur Foundation Research Network on Socioeconomic Status & Health. Preparation of the manuscript was supported by grants from the National Heart, Lung, and Blood Institute ( 1R01HL127260-01 ; 1F32HL131353 ).
Publisher Copyright:
© 2016 Elsevier Ltd
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Hostility and adverse health outcomes are inconsistently associated in the literature. Self-regulation and cortisol secretion may play important roles in differentiating those hostile individuals who are at greater risk of negative health outcomes from those who are not. In the present study, we sought to examine if having high self-regulatory strength, as indexed by high stress-induced high-frequency heart rate variability (HF-HRV), buffered the effects of hostility on cortisol secretion. Participants (N = 213) completed a self-report measure of hostility and measurement of HF-HRV at rest and during a social stress task. Saliva samples were collected immediately before (one sample), and over a 50 min period after (six samples), the stress task to evaluate cortisol secretion over time. Hostile individuals were less likely to demonstrate cortisol sensitivity (i.e., high change in cortisol over time) when they had high stress-induced HF-HRV. Such findings are important given that cortisol sensitivity increases risk of metabolic and inflammatory disorders via glucocorticoid resistance and inflammation. Therefore, interventions that increase stress-induced HF-HRV may reduce the impact of hostility on health outcomes.
AB - Hostility and adverse health outcomes are inconsistently associated in the literature. Self-regulation and cortisol secretion may play important roles in differentiating those hostile individuals who are at greater risk of negative health outcomes from those who are not. In the present study, we sought to examine if having high self-regulatory strength, as indexed by high stress-induced high-frequency heart rate variability (HF-HRV), buffered the effects of hostility on cortisol secretion. Participants (N = 213) completed a self-report measure of hostility and measurement of HF-HRV at rest and during a social stress task. Saliva samples were collected immediately before (one sample), and over a 50 min period after (six samples), the stress task to evaluate cortisol secretion over time. Hostile individuals were less likely to demonstrate cortisol sensitivity (i.e., high change in cortisol over time) when they had high stress-induced HF-HRV. Such findings are important given that cortisol sensitivity increases risk of metabolic and inflammatory disorders via glucocorticoid resistance and inflammation. Therefore, interventions that increase stress-induced HF-HRV may reduce the impact of hostility on health outcomes.
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U2 - 10.1016/j.psyneuen.2016.10.014
DO - 10.1016/j.psyneuen.2016.10.014
M3 - Article
C2 - 27838516
AN - SCOPUS:84994716125
VL - 75
SP - 222
EP - 227
JO - Psychoneuroendocrinology
JF - Psychoneuroendocrinology
SN - 0306-4530
ER -