Abstract
The journey of gene transfer from laboratory to clinic has been slow and fraught with many challenges and barriers. Despite the development of the initial technology in the early 1970s, a standard clinical treatment involving "gene therapy" remains to be seen. Furthermore, much was written about the technology in the early 1990s, but since then, not much has been written about the journey of gene transfer. The translational path of gene transfer thus far, both pitfalls and successes, can serve as a study not only in navigating ethical and safety concerns, but also in the importance of scientist-public interactions. Here, we examine the translational progress of gene transfer and what can be gleaned from its history.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 279-281 |
| Number of pages | 3 |
| Journal | Clinical and Translational Science |
| Volume | 4 |
| Issue number | 4 |
| DOIs |
|
| State | Published - Aug 1 2011 |
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All Science Journal Classification (ASJC) codes
- Neuroscience(all)
- Biochemistry, Genetics and Molecular Biology(all)
- Pharmacology, Toxicology and Pharmaceutics(all)
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Translating Gene Transfer : A Stalled Effort. / Greenberg, Alexandra J.; McCormick, Jennifer; Tapia, Carmen J.; Windebank, Anthony J.
In: Clinical and Translational Science, Vol. 4, No. 4, 01.08.2011, p. 279-281.Research output: Contribution to journal › Comment/debate
TY - JOUR
T1 - Translating Gene Transfer
T2 - A Stalled Effort
AU - Greenberg, Alexandra J.
AU - McCormick, Jennifer
AU - Tapia, Carmen J.
AU - Windebank, Anthony J.
PY - 2011/8/1
Y1 - 2011/8/1
N2 - The journey of gene transfer from laboratory to clinic has been slow and fraught with many challenges and barriers. Despite the development of the initial technology in the early 1970s, a standard clinical treatment involving "gene therapy" remains to be seen. Furthermore, much was written about the technology in the early 1990s, but since then, not much has been written about the journey of gene transfer. The translational path of gene transfer thus far, both pitfalls and successes, can serve as a study not only in navigating ethical and safety concerns, but also in the importance of scientist-public interactions. Here, we examine the translational progress of gene transfer and what can be gleaned from its history.
AB - The journey of gene transfer from laboratory to clinic has been slow and fraught with many challenges and barriers. Despite the development of the initial technology in the early 1970s, a standard clinical treatment involving "gene therapy" remains to be seen. Furthermore, much was written about the technology in the early 1990s, but since then, not much has been written about the journey of gene transfer. The translational path of gene transfer thus far, both pitfalls and successes, can serve as a study not only in navigating ethical and safety concerns, but also in the importance of scientist-public interactions. Here, we examine the translational progress of gene transfer and what can be gleaned from its history.
UR - http://www.scopus.com/inward/record.url?scp=80052235170&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=80052235170&partnerID=8YFLogxK
U2 - 10.1111/j.1752-8062.2011.00297.x
DO - 10.1111/j.1752-8062.2011.00297.x
M3 - Comment/debate
C2 - 21884516
AN - SCOPUS:80052235170
VL - 4
SP - 279
EP - 281
JO - Clinical and Translational Science
JF - Clinical and Translational Science
SN - 1752-8054
IS - 4
ER -