Transmission of louping ill virus between infected and uninfected ticks co-feeding on mountain hares

Linda D. Jones, Michael Gaunt, Rosie S. Hails, Karen Laurenson, Peter J. Hudson, Hugh Reid, Pauline Henbest, Ernest A. Gould

Research output: Contribution to journalArticle

73 Citations (Scopus)

Abstract

Most of the data on oral infection of ticks by louping ill virus have been obtained from experiments in which animals were infected by syringe inoculation with infectious material. Using infected ticks to mimic the natural situation, we have demonstrated that 1ouping ill (LI) virus transmission can occur from infected to uninfected Ixodes ricinus feeding in close proximity on mountain hares (Lepus timidus). Under these conditions the hares developed either low or undetectable viraemias. Highest prevalence of LI virus infection was observed in recipient nymphs which had fed to repletion between days 3 and 7 post-attachment of virus-infected adults; following engorgement, 56% of nymphs acquired virus. These results demonstrate the efficient transmission of LI virus between co-feeding ticks on naive mountain hares. However, when ticks were allowed to co-feed on virus-immune hares a significant reduction in the frequency of infection was observed. Neither red deer (Cervus elaphus) nor New Zealand White rabbits supported transmission of LI virus. The significance of virus transmission between cofeeding ticks on LI virus epidemiology is discussed.

Original languageEnglish (US)
Pages (from-to)172-176
Number of pages5
JournalMedical and Veterinary Entomology
Volume11
Issue number2
DOIs
StatePublished - Apr 1997

Fingerprint

Louping ill virus
Tick-Borne Encephalitis Viruses
Hares
tick
hares
Ticks
virus transmission
ticks
virus
mountains
Viruses
viruses
mountain
Cervus elaphus
Nymph
nymphs
Lepus timidus
infection
engorgement
Ixodes ricinus

All Science Journal Classification (ASJC) codes

  • Parasitology
  • Ecology, Evolution, Behavior and Systematics
  • veterinary(all)
  • Insect Science

Cite this

Jones, Linda D. ; Gaunt, Michael ; Hails, Rosie S. ; Laurenson, Karen ; Hudson, Peter J. ; Reid, Hugh ; Henbest, Pauline ; Gould, Ernest A. / Transmission of louping ill virus between infected and uninfected ticks co-feeding on mountain hares. In: Medical and Veterinary Entomology. 1997 ; Vol. 11, No. 2. pp. 172-176.
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Transmission of louping ill virus between infected and uninfected ticks co-feeding on mountain hares. / Jones, Linda D.; Gaunt, Michael; Hails, Rosie S.; Laurenson, Karen; Hudson, Peter J.; Reid, Hugh; Henbest, Pauline; Gould, Ernest A.

In: Medical and Veterinary Entomology, Vol. 11, No. 2, 04.1997, p. 172-176.

Research output: Contribution to journalArticle

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