Treatment of cushing’s disease with bilateral adrenalectomy and autotransplantation

M. D. Urban, Peter Lee, R. K. Danish, C. J. Migeon

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Abstract

2 Cases of childhood Cushing’s disease have been treated with bilateral adrenalectomy and autotransplantation of adrenal tissue. Transplantation was unsuccessful in 1 case. In the other patient, replacement therapy was discontinued without any symptoms of hypo- or hyperadrenocorticism. Her urinary 17-hydroxycorticosteroids, free cortisol and aldosterone remain in the low normal range indicating functional adrenal tissue, probably a result of the transplant.

Original languageEnglish (US)
Pages (from-to)81-89
Number of pages9
JournalHormone Research in Paediatrics
Volume13
Issue number2
DOIs
StatePublished - Jan 1 1980

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All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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