Inteleurkin-22 (IL-22) is a IL-10 family cytokine member and is mainly produced by innate lymphoid cells (ILCs), Th17 cells, and Th22 cells. Previous studies have indicated that IL-23 and several transcription factors, including STAT3, RORγt, and the AhR are important stimulus. Recently, there is emerging evidence that Tregs can regulate IL-22 expression. In the review, we discuss the updated advancement on Tregs function and its regulatory role on IL-22 expression.
|Original language||English (US)|
|Number of pages||7|
|Journal||International Journal of Clinical and Experimental Pathology|
|State||Published - 2014|
All Science Journal Classification (ASJC) codes
- Pathology and Forensic Medicine