TY - JOUR
T1 - Treg cells
T2 - A potential regulator for IL-22 expression?
AU - Lin, Shuman
AU - Yang, Xuyan
AU - Liang, Dian
AU - Zheng, Song Guo
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 2014
Y1 - 2014
N2 - Inteleurkin-22 (IL-22) is a IL-10 family cytokine member and is mainly produced by innate lymphoid cells (ILCs), Th17 cells, and Th22 cells. Previous studies have indicated that IL-23 and several transcription factors, including STAT3, RORγt, and the AhR are important stimulus. Recently, there is emerging evidence that Tregs can regulate IL-22 expression. In the review, we discuss the updated advancement on Tregs function and its regulatory role on IL-22 expression.
AB - Inteleurkin-22 (IL-22) is a IL-10 family cytokine member and is mainly produced by innate lymphoid cells (ILCs), Th17 cells, and Th22 cells. Previous studies have indicated that IL-23 and several transcription factors, including STAT3, RORγt, and the AhR are important stimulus. Recently, there is emerging evidence that Tregs can regulate IL-22 expression. In the review, we discuss the updated advancement on Tregs function and its regulatory role on IL-22 expression.
UR - http://www.scopus.com/inward/record.url?scp=84894086378&partnerID=8YFLogxK
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M3 - Review article
C2 - 24551268
AN - SCOPUS:84894086378
VL - 7
SP - 474
EP - 480
JO - International Journal of Clinical and Experimental Pathology
JF - International Journal of Clinical and Experimental Pathology
SN - 1936-2625
IS - 2
ER -