Trigeminal neuralgia

Mechanisms of treatment

Research output: Contribution to journalReview article

37 Citations (Scopus)

Abstract

Background: Mechanisms of the surgical treatment of trigeminal neuralgia are considered. Results: Trigeminal neuralgia is effectively treated by microvascular decompression (MVD) and other surgical procedures. These procedures often cause reactivation of herpes simplex virus (HSV), which is latent in trigeminal ganglion neurons. Conclusion: MVD and other surgical procedures alter ganglion neuron transcription, as indicated by HSV reactivation. Controlled injury of the trigeminal root-ganglion probably occurs with the disparate surgical procedures, and this is likely the means of their effectiveness.

Original languageEnglish (US)
Pages (from-to)17-19
Number of pages3
JournalNeurology
Volume51
Issue number1
DOIs
StatePublished - Jan 1 1998

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Trigeminal Neuralgia
Microvascular Decompression Surgery
Trigeminal Ganglion
Simplexvirus
Neurons
Ganglia
Wounds and Injuries

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

Cite this

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title = "Trigeminal neuralgia: Mechanisms of treatment",
abstract = "Background: Mechanisms of the surgical treatment of trigeminal neuralgia are considered. Results: Trigeminal neuralgia is effectively treated by microvascular decompression (MVD) and other surgical procedures. These procedures often cause reactivation of herpes simplex virus (HSV), which is latent in trigeminal ganglion neurons. Conclusion: MVD and other surgical procedures alter ganglion neuron transcription, as indicated by HSV reactivation. Controlled injury of the trigeminal root-ganglion probably occurs with the disparate surgical procedures, and this is likely the means of their effectiveness.",
author = "Richard Tenser",
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doi = "10.1212/WNL.51.1.17",
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}

Trigeminal neuralgia : Mechanisms of treatment. / Tenser, Richard.

In: Neurology, Vol. 51, No. 1, 01.01.1998, p. 17-19.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Trigeminal neuralgia

T2 - Mechanisms of treatment

AU - Tenser, Richard

PY - 1998/1/1

Y1 - 1998/1/1

N2 - Background: Mechanisms of the surgical treatment of trigeminal neuralgia are considered. Results: Trigeminal neuralgia is effectively treated by microvascular decompression (MVD) and other surgical procedures. These procedures often cause reactivation of herpes simplex virus (HSV), which is latent in trigeminal ganglion neurons. Conclusion: MVD and other surgical procedures alter ganglion neuron transcription, as indicated by HSV reactivation. Controlled injury of the trigeminal root-ganglion probably occurs with the disparate surgical procedures, and this is likely the means of their effectiveness.

AB - Background: Mechanisms of the surgical treatment of trigeminal neuralgia are considered. Results: Trigeminal neuralgia is effectively treated by microvascular decompression (MVD) and other surgical procedures. These procedures often cause reactivation of herpes simplex virus (HSV), which is latent in trigeminal ganglion neurons. Conclusion: MVD and other surgical procedures alter ganglion neuron transcription, as indicated by HSV reactivation. Controlled injury of the trigeminal root-ganglion probably occurs with the disparate surgical procedures, and this is likely the means of their effectiveness.

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U2 - 10.1212/WNL.51.1.17

DO - 10.1212/WNL.51.1.17

M3 - Review article

VL - 51

SP - 17

EP - 19

JO - Neurology

JF - Neurology

SN - 0028-3878

IS - 1

ER -