Troponin elevations in patients with chronic cardiovascular disease: An analysis of current evidence and significance

Archer Martin, Anita Malhotra, Breandan Sullivan, Harish Ramakrishna

Research output: Contribution to journalReview article

4 Citations (Scopus)

Abstract

Serum troponin elevation above the 99th percentile of the upper reference limit in healthy subjects (<0.01 ng/ml measured using currently available high.sensitivity cardiac troponin laboratory assays) is required to establish the diagnosis the diagnosis of myocardial necrosis in acute cardiovascular syndromes, as well as guide prognosis and therapy. In the perioperative period, for patients with cardiac disease undergoing noncardiac surgery, it is a particularly critical biomarker universally used to assess the myocardial damage. The value of troponin testing and elevation (as well as its significance) in patients with chronic cardiac valvular, vascular, and renal disease is relatively less well understood. This evidence.based review seeks to examine the currently available data assessing the significance of troponin elevation in certain chronic valvular and other disease states.

Original languageEnglish (US)
Pages (from-to)321-327
Number of pages7
JournalAnnals of Cardiac Anaesthesia
Volume19
Issue number2
DOIs
StatePublished - Apr 1 2016

Fingerprint

Troponin
Chronic Disease
Cardiovascular Diseases
Perioperative Period
Vascular Diseases
Heart Diseases
Healthy Volunteers
Necrosis
Biomarkers
Kidney
Serum
Therapeutics

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Anesthesiology and Pain Medicine

Cite this

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abstract = "Serum troponin elevation above the 99th percentile of the upper reference limit in healthy subjects (<0.01 ng/ml measured using currently available high.sensitivity cardiac troponin laboratory assays) is required to establish the diagnosis the diagnosis of myocardial necrosis in acute cardiovascular syndromes, as well as guide prognosis and therapy. In the perioperative period, for patients with cardiac disease undergoing noncardiac surgery, it is a particularly critical biomarker universally used to assess the myocardial damage. The value of troponin testing and elevation (as well as its significance) in patients with chronic cardiac valvular, vascular, and renal disease is relatively less well understood. This evidence.based review seeks to examine the currently available data assessing the significance of troponin elevation in certain chronic valvular and other disease states.",
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Troponin elevations in patients with chronic cardiovascular disease : An analysis of current evidence and significance. / Martin, Archer; Malhotra, Anita; Sullivan, Breandan; Ramakrishna, Harish.

In: Annals of Cardiac Anaesthesia, Vol. 19, No. 2, 01.04.2016, p. 321-327.

Research output: Contribution to journalReview article

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