Tumours in white suckers from Lake Michigan tributaries

pathology and prevalence

Vicki Suzette Blazer, H. L. Walsh, R. P. Braham, C. M. Hahn, P. Mazik, P. B. McIntyre

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

The prevalence and histopathology of neoplastic lesions were assessed in white sucker Catostomus commersonii captured at two Lake Michigan Areas of Concern (AOCs), the Sheboygan River and Milwaukee Estuary. Findings were compared to those observed at two non-AOC sites, the Root and Kewaunee rivers. At each site, approximately 200 adult suckers were collected during their spawning migration. Raised skin lesions were observed at all sites and included discrete white spots, mucoid plaques on the body surface and fins and large papillomatous lesions on lips and body. Microscopically, hyperplasia, papilloma and squamous cell carcinoma were documented. Liver neoplasms were also observed at all sites and included both hepatocellular and biliary tumours. Based on land use, the Kewaunee River was the site least impacted by human activities previously associated with fish tumours and had significantly fewer liver neoplasms when compared to the other sites. The proportion of white suckers with liver tumours followed the same patterns as the proportion of urban land use in the watershed: the Milwaukee Estuary had the highest prevalence, followed by the Root, Sheboygan and Kewaunee rivers. The overall skin neoplasm (papilloma and carcinoma) prevalence did not follow the same pattern, although the percentage of white suckers with squamous cell carcinoma exhibited a similar relationship to land use. Testicular tumours (seminoma) were observed at both AOC sites but not at the non-AOC sites. Both skin and liver tumours were significantly and positively associated with age but not sex.

Original languageEnglish (US)
Pages (from-to)377-393
Number of pages17
JournalJournal of Fish Diseases
Volume40
Issue number3
DOIs
StatePublished - Mar 1 2017

Fingerprint

Lake Michigan
liver neoplasms
pathology
Lakes
Rivers
tumor
tributary
Pathology
Estuaries
rivers
papilloma
neoplasms
lesion
land use
squamous cell carcinoma
lake
Papilloma
Liver Neoplasms
skin
lesions (animal)

All Science Journal Classification (ASJC) codes

  • Aquatic Science
  • veterinary (miscalleneous)

Cite this

Blazer, V. S., Walsh, H. L., Braham, R. P., Hahn, C. M., Mazik, P., & McIntyre, P. B. (2017). Tumours in white suckers from Lake Michigan tributaries: pathology and prevalence. Journal of Fish Diseases, 40(3), 377-393. https://doi.org/10.1111/jfd.12520
Blazer, Vicki Suzette ; Walsh, H. L. ; Braham, R. P. ; Hahn, C. M. ; Mazik, P. ; McIntyre, P. B. / Tumours in white suckers from Lake Michigan tributaries : pathology and prevalence. In: Journal of Fish Diseases. 2017 ; Vol. 40, No. 3. pp. 377-393.
@article{7a322d9f3d5d4baf96dc562b84d6b700,
title = "Tumours in white suckers from Lake Michigan tributaries: pathology and prevalence",
abstract = "The prevalence and histopathology of neoplastic lesions were assessed in white sucker Catostomus commersonii captured at two Lake Michigan Areas of Concern (AOCs), the Sheboygan River and Milwaukee Estuary. Findings were compared to those observed at two non-AOC sites, the Root and Kewaunee rivers. At each site, approximately 200 adult suckers were collected during their spawning migration. Raised skin lesions were observed at all sites and included discrete white spots, mucoid plaques on the body surface and fins and large papillomatous lesions on lips and body. Microscopically, hyperplasia, papilloma and squamous cell carcinoma were documented. Liver neoplasms were also observed at all sites and included both hepatocellular and biliary tumours. Based on land use, the Kewaunee River was the site least impacted by human activities previously associated with fish tumours and had significantly fewer liver neoplasms when compared to the other sites. The proportion of white suckers with liver tumours followed the same patterns as the proportion of urban land use in the watershed: the Milwaukee Estuary had the highest prevalence, followed by the Root, Sheboygan and Kewaunee rivers. The overall skin neoplasm (papilloma and carcinoma) prevalence did not follow the same pattern, although the percentage of white suckers with squamous cell carcinoma exhibited a similar relationship to land use. Testicular tumours (seminoma) were observed at both AOC sites but not at the non-AOC sites. Both skin and liver tumours were significantly and positively associated with age but not sex.",
author = "Blazer, {Vicki Suzette} and Walsh, {H. L.} and Braham, {R. P.} and Hahn, {C. M.} and P. Mazik and McIntyre, {P. B.}",
year = "2017",
month = "3",
day = "1",
doi = "10.1111/jfd.12520",
language = "English (US)",
volume = "40",
pages = "377--393",
journal = "Journal of Fish Diseases",
issn = "0140-7775",
publisher = "Wiley-Blackwell",
number = "3",

}

Blazer, VS, Walsh, HL, Braham, RP, Hahn, CM, Mazik, P & McIntyre, PB 2017, 'Tumours in white suckers from Lake Michigan tributaries: pathology and prevalence', Journal of Fish Diseases, vol. 40, no. 3, pp. 377-393. https://doi.org/10.1111/jfd.12520

Tumours in white suckers from Lake Michigan tributaries : pathology and prevalence. / Blazer, Vicki Suzette; Walsh, H. L.; Braham, R. P.; Hahn, C. M.; Mazik, P.; McIntyre, P. B.

In: Journal of Fish Diseases, Vol. 40, No. 3, 01.03.2017, p. 377-393.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Tumours in white suckers from Lake Michigan tributaries

T2 - pathology and prevalence

AU - Blazer, Vicki Suzette

AU - Walsh, H. L.

AU - Braham, R. P.

AU - Hahn, C. M.

AU - Mazik, P.

AU - McIntyre, P. B.

PY - 2017/3/1

Y1 - 2017/3/1

N2 - The prevalence and histopathology of neoplastic lesions were assessed in white sucker Catostomus commersonii captured at two Lake Michigan Areas of Concern (AOCs), the Sheboygan River and Milwaukee Estuary. Findings were compared to those observed at two non-AOC sites, the Root and Kewaunee rivers. At each site, approximately 200 adult suckers were collected during their spawning migration. Raised skin lesions were observed at all sites and included discrete white spots, mucoid plaques on the body surface and fins and large papillomatous lesions on lips and body. Microscopically, hyperplasia, papilloma and squamous cell carcinoma were documented. Liver neoplasms were also observed at all sites and included both hepatocellular and biliary tumours. Based on land use, the Kewaunee River was the site least impacted by human activities previously associated with fish tumours and had significantly fewer liver neoplasms when compared to the other sites. The proportion of white suckers with liver tumours followed the same patterns as the proportion of urban land use in the watershed: the Milwaukee Estuary had the highest prevalence, followed by the Root, Sheboygan and Kewaunee rivers. The overall skin neoplasm (papilloma and carcinoma) prevalence did not follow the same pattern, although the percentage of white suckers with squamous cell carcinoma exhibited a similar relationship to land use. Testicular tumours (seminoma) were observed at both AOC sites but not at the non-AOC sites. Both skin and liver tumours were significantly and positively associated with age but not sex.

AB - The prevalence and histopathology of neoplastic lesions were assessed in white sucker Catostomus commersonii captured at two Lake Michigan Areas of Concern (AOCs), the Sheboygan River and Milwaukee Estuary. Findings were compared to those observed at two non-AOC sites, the Root and Kewaunee rivers. At each site, approximately 200 adult suckers were collected during their spawning migration. Raised skin lesions were observed at all sites and included discrete white spots, mucoid plaques on the body surface and fins and large papillomatous lesions on lips and body. Microscopically, hyperplasia, papilloma and squamous cell carcinoma were documented. Liver neoplasms were also observed at all sites and included both hepatocellular and biliary tumours. Based on land use, the Kewaunee River was the site least impacted by human activities previously associated with fish tumours and had significantly fewer liver neoplasms when compared to the other sites. The proportion of white suckers with liver tumours followed the same patterns as the proportion of urban land use in the watershed: the Milwaukee Estuary had the highest prevalence, followed by the Root, Sheboygan and Kewaunee rivers. The overall skin neoplasm (papilloma and carcinoma) prevalence did not follow the same pattern, although the percentage of white suckers with squamous cell carcinoma exhibited a similar relationship to land use. Testicular tumours (seminoma) were observed at both AOC sites but not at the non-AOC sites. Both skin and liver tumours were significantly and positively associated with age but not sex.

UR - http://www.scopus.com/inward/record.url?scp=84983424316&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84983424316&partnerID=8YFLogxK

U2 - 10.1111/jfd.12520

DO - 10.1111/jfd.12520

M3 - Article

VL - 40

SP - 377

EP - 393

JO - Journal of Fish Diseases

JF - Journal of Fish Diseases

SN - 0140-7775

IS - 3

ER -

Blazer VS, Walsh HL, Braham RP, Hahn CM, Mazik P, McIntyre PB. Tumours in white suckers from Lake Michigan tributaries: pathology and prevalence. Journal of Fish Diseases. 2017 Mar 1;40(3):377-393. https://doi.org/10.1111/jfd.12520