Two novel promoters in the upstream regulatory region of human papillomavirus type 31b are negatively regulated by epithelial differentiation

Michelle A. Ozbun, Craig Meyers

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Organotypic cultures support the stratification and differentiation of keratinocytes and the human papillomavirus (HPV) life cycle. We report transcription from four novel promoters in the HPV31b upstream regulatory region during the viral life cycle in organotypic cultures. Promoter initiation was not differentiation dependent; two promoters were down- regulated upon epithelial differentiation.

Original languageEnglish (US)
Pages (from-to)3505-3510
Number of pages6
JournalJournal of virology
Volume73
Issue number4
StatePublished - Apr 1 1999

Fingerprint

Papillomaviridae
Nucleic Acid Regulatory Sequences
keratinocytes
Life Cycle Stages
Keratinocytes

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

Cite this

@article{3fab8f5931e240fb9604229bd049071d,
title = "Two novel promoters in the upstream regulatory region of human papillomavirus type 31b are negatively regulated by epithelial differentiation",
abstract = "Organotypic cultures support the stratification and differentiation of keratinocytes and the human papillomavirus (HPV) life cycle. We report transcription from four novel promoters in the HPV31b upstream regulatory region during the viral life cycle in organotypic cultures. Promoter initiation was not differentiation dependent; two promoters were down- regulated upon epithelial differentiation.",
author = "Ozbun, {Michelle A.} and Craig Meyers",
year = "1999",
month = "4",
day = "1",
language = "English (US)",
volume = "73",
pages = "3505--3510",
journal = "Journal of Virology",
issn = "0022-538X",
publisher = "American Society for Microbiology",
number = "4",

}

Two novel promoters in the upstream regulatory region of human papillomavirus type 31b are negatively regulated by epithelial differentiation. / Ozbun, Michelle A.; Meyers, Craig.

In: Journal of virology, Vol. 73, No. 4, 01.04.1999, p. 3505-3510.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Two novel promoters in the upstream regulatory region of human papillomavirus type 31b are negatively regulated by epithelial differentiation

AU - Ozbun, Michelle A.

AU - Meyers, Craig

PY - 1999/4/1

Y1 - 1999/4/1

N2 - Organotypic cultures support the stratification and differentiation of keratinocytes and the human papillomavirus (HPV) life cycle. We report transcription from four novel promoters in the HPV31b upstream regulatory region during the viral life cycle in organotypic cultures. Promoter initiation was not differentiation dependent; two promoters were down- regulated upon epithelial differentiation.

AB - Organotypic cultures support the stratification and differentiation of keratinocytes and the human papillomavirus (HPV) life cycle. We report transcription from four novel promoters in the HPV31b upstream regulatory region during the viral life cycle in organotypic cultures. Promoter initiation was not differentiation dependent; two promoters were down- regulated upon epithelial differentiation.

UR - http://www.scopus.com/inward/record.url?scp=0032976578&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032976578&partnerID=8YFLogxK

M3 - Article

C2 - 10074210

AN - SCOPUS:0032976578

VL - 73

SP - 3505

EP - 3510

JO - Journal of Virology

JF - Journal of Virology

SN - 0022-538X

IS - 4

ER -