Two novel promoters in the upstream regulatory region of human papillomavirus type 31b are negatively regulated by epithelial differentiation

Michelle A. Ozbun, Craig Meyers

Research output: Contribution to journalArticle

30 Scopus citations

Abstract

Organotypic cultures support the stratification and differentiation of keratinocytes and the human papillomavirus (HPV) life cycle. We report transcription from four novel promoters in the HPV31b upstream regulatory region during the viral life cycle in organotypic cultures. Promoter initiation was not differentiation dependent; two promoters were down- regulated upon epithelial differentiation.

Original languageEnglish (US)
Pages (from-to)3505-3510
Number of pages6
JournalJournal of virology
Volume73
Issue number4
StatePublished - Apr 1 1999

All Science Journal Classification (ASJC) codes

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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