UKF-based adaptive electric fields control of desynchronization for the PR model under the ephaptic transmission

Xile Wei, Jian Cheng, Jiang Wang, Bin Deng, Meili Lu, Yanqiu Che

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The applied electric field (EF) has shown to have great influence on epileptiform firing. Epilepsy is a dynamical disease charactered by hypersynchronous firing. Taking the electrical characteristic of extracellular medium i.e. ephaptic transmission into consideration, we build a PR model in the presence of the applied electric field. V̄ DS out is the DC part of the voltage between soma and dendrite that electric field takes effect on PR neuron. In this paper we find V̄ DS out is the key parameter that affects the neuronal synchronization and use Unscented Kalman Filter (UKF) to estimate it, then based on key parameter we design a closed-loop control to desynchronize neuronal firing. It is found that the control can not only desynchronize neuronal network, but also can adjust the strength of applied electric field according to the degree of synchronization.

Original languageEnglish (US)
Title of host publicationProceedings of the 2012 24th Chinese Control and Decision Conference, CCDC 2012
Pages2439-2444
Number of pages6
DOIs
StatePublished - Oct 1 2012
Event2012 24th Chinese Control and Decision Conference, CCDC 2012 - Taiyuan, China
Duration: May 23 2012May 25 2012

Publication series

NameProceedings of the 2012 24th Chinese Control and Decision Conference, CCDC 2012

Other

Other2012 24th Chinese Control and Decision Conference, CCDC 2012
CountryChina
CityTaiyuan
Period5/23/125/25/12

Fingerprint

Kalman filters
Electric fields
Synchronization
Neurons
Kalman filter
Electric potential

All Science Journal Classification (ASJC) codes

  • Information Systems and Management
  • Control and Systems Engineering

Cite this

Wei, X., Cheng, J., Wang, J., Deng, B., Lu, M., & Che, Y. (2012). UKF-based adaptive electric fields control of desynchronization for the PR model under the ephaptic transmission. In Proceedings of the 2012 24th Chinese Control and Decision Conference, CCDC 2012 (pp. 2439-2444). [6244389] (Proceedings of the 2012 24th Chinese Control and Decision Conference, CCDC 2012). https://doi.org/10.1109/CCDC.2012.6244389
Wei, Xile ; Cheng, Jian ; Wang, Jiang ; Deng, Bin ; Lu, Meili ; Che, Yanqiu. / UKF-based adaptive electric fields control of desynchronization for the PR model under the ephaptic transmission. Proceedings of the 2012 24th Chinese Control and Decision Conference, CCDC 2012. 2012. pp. 2439-2444 (Proceedings of the 2012 24th Chinese Control and Decision Conference, CCDC 2012).
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Wei, X, Cheng, J, Wang, J, Deng, B, Lu, M & Che, Y 2012, UKF-based adaptive electric fields control of desynchronization for the PR model under the ephaptic transmission. in Proceedings of the 2012 24th Chinese Control and Decision Conference, CCDC 2012., 6244389, Proceedings of the 2012 24th Chinese Control and Decision Conference, CCDC 2012, pp. 2439-2444, 2012 24th Chinese Control and Decision Conference, CCDC 2012, Taiyuan, China, 5/23/12. https://doi.org/10.1109/CCDC.2012.6244389

UKF-based adaptive electric fields control of desynchronization for the PR model under the ephaptic transmission. / Wei, Xile; Cheng, Jian; Wang, Jiang; Deng, Bin; Lu, Meili; Che, Yanqiu.

Proceedings of the 2012 24th Chinese Control and Decision Conference, CCDC 2012. 2012. p. 2439-2444 6244389 (Proceedings of the 2012 24th Chinese Control and Decision Conference, CCDC 2012).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Wei X, Cheng J, Wang J, Deng B, Lu M, Che Y. UKF-based adaptive electric fields control of desynchronization for the PR model under the ephaptic transmission. In Proceedings of the 2012 24th Chinese Control and Decision Conference, CCDC 2012. 2012. p. 2439-2444. 6244389. (Proceedings of the 2012 24th Chinese Control and Decision Conference, CCDC 2012). https://doi.org/10.1109/CCDC.2012.6244389