Ultrasonic absorption in deer blood

K. K. Shung, James Ballard

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

It has been shown that ultrasonic absorption of sickle cells obtained from human patients can be correlated with the aggregation state of sickle cell hemoglobin within the intact cells. We have extended this investigation to red blood cells obtained from white-tailed deer which also exhibit the sickling phenomenon. In contrast to the sickling phenomenon in humans, the sickling of deer erythrocytes occurs when the oxygen tension and pH of the blood are high. Nevertheless, remarkable similarities exist between the process of hemoglobin polymerization which produces sickling in both species. We have measured the ultrasonic absorption as a function of blood pH and oxygen tension and compare it with the morphological changes. High pH and oxygen tension which enhance sickling caused an increase in ultrasonic absorption. Low pH and low oxygen tension which retard sickling reduced ultrasonic absorption. The magnitude of the change in ultrasonic specific absorption coefficient under extreme conditions has been found to be more than two fold at a frequency of 15 MHz.

Original languageEnglish (US)
Pages (from-to)664-668
Number of pages5
JournalJournal of the Acoustical Society of America
Volume70
Issue number3
DOIs
StatePublished - Jan 1 1981

Fingerprint

deer
oxygen tension
blood
ultrasonics
hemoglobin
erythrocytes
cells
absorptivity
polymerization
Blood
Deer
Cells
Oxygen

All Science Journal Classification (ASJC) codes

  • Arts and Humanities (miscellaneous)
  • Acoustics and Ultrasonics

Cite this

Shung, K. K. ; Ballard, James. / Ultrasonic absorption in deer blood. In: Journal of the Acoustical Society of America. 1981 ; Vol. 70, No. 3. pp. 664-668.
@article{7b8ec2ece0ef4b50b9deb25babb6aca5,
title = "Ultrasonic absorption in deer blood",
abstract = "It has been shown that ultrasonic absorption of sickle cells obtained from human patients can be correlated with the aggregation state of sickle cell hemoglobin within the intact cells. We have extended this investigation to red blood cells obtained from white-tailed deer which also exhibit the sickling phenomenon. In contrast to the sickling phenomenon in humans, the sickling of deer erythrocytes occurs when the oxygen tension and pH of the blood are high. Nevertheless, remarkable similarities exist between the process of hemoglobin polymerization which produces sickling in both species. We have measured the ultrasonic absorption as a function of blood pH and oxygen tension and compare it with the morphological changes. High pH and oxygen tension which enhance sickling caused an increase in ultrasonic absorption. Low pH and low oxygen tension which retard sickling reduced ultrasonic absorption. The magnitude of the change in ultrasonic specific absorption coefficient under extreme conditions has been found to be more than two fold at a frequency of 15 MHz.",
author = "Shung, {K. K.} and James Ballard",
year = "1981",
month = "1",
day = "1",
doi = "10.1121/1.386928",
language = "English (US)",
volume = "70",
pages = "664--668",
journal = "Journal of the Acoustical Society of America",
issn = "0001-4966",
publisher = "Acoustical Society of America",
number = "3",

}

Ultrasonic absorption in deer blood. / Shung, K. K.; Ballard, James.

In: Journal of the Acoustical Society of America, Vol. 70, No. 3, 01.01.1981, p. 664-668.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Ultrasonic absorption in deer blood

AU - Shung, K. K.

AU - Ballard, James

PY - 1981/1/1

Y1 - 1981/1/1

N2 - It has been shown that ultrasonic absorption of sickle cells obtained from human patients can be correlated with the aggregation state of sickle cell hemoglobin within the intact cells. We have extended this investigation to red blood cells obtained from white-tailed deer which also exhibit the sickling phenomenon. In contrast to the sickling phenomenon in humans, the sickling of deer erythrocytes occurs when the oxygen tension and pH of the blood are high. Nevertheless, remarkable similarities exist between the process of hemoglobin polymerization which produces sickling in both species. We have measured the ultrasonic absorption as a function of blood pH and oxygen tension and compare it with the morphological changes. High pH and oxygen tension which enhance sickling caused an increase in ultrasonic absorption. Low pH and low oxygen tension which retard sickling reduced ultrasonic absorption. The magnitude of the change in ultrasonic specific absorption coefficient under extreme conditions has been found to be more than two fold at a frequency of 15 MHz.

AB - It has been shown that ultrasonic absorption of sickle cells obtained from human patients can be correlated with the aggregation state of sickle cell hemoglobin within the intact cells. We have extended this investigation to red blood cells obtained from white-tailed deer which also exhibit the sickling phenomenon. In contrast to the sickling phenomenon in humans, the sickling of deer erythrocytes occurs when the oxygen tension and pH of the blood are high. Nevertheless, remarkable similarities exist between the process of hemoglobin polymerization which produces sickling in both species. We have measured the ultrasonic absorption as a function of blood pH and oxygen tension and compare it with the morphological changes. High pH and oxygen tension which enhance sickling caused an increase in ultrasonic absorption. Low pH and low oxygen tension which retard sickling reduced ultrasonic absorption. The magnitude of the change in ultrasonic specific absorption coefficient under extreme conditions has been found to be more than two fold at a frequency of 15 MHz.

UR - http://www.scopus.com/inward/record.url?scp=0019611899&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019611899&partnerID=8YFLogxK

U2 - 10.1121/1.386928

DO - 10.1121/1.386928

M3 - Article

AN - SCOPUS:0019611899

VL - 70

SP - 664

EP - 668

JO - Journal of the Acoustical Society of America

JF - Journal of the Acoustical Society of America

SN - 0001-4966

IS - 3

ER -