TY - JOUR
T1 - Underrepresentation of women in new drug trials. Ramifications and remedies
AU - Kinney, E. L.
AU - Trautmann, J.
AU - Gold, J. A.
AU - Vesell, E. S.
AU - Zelis, R.
PY - 1981/1/1
Y1 - 1981/1/1
N2 - Young women serve less frequently than young men as subjects in premarketing clinical drug trials. Moral, legal, and medical implications of this underrepresentation of women are considered. Risks of medical harm to female patients can increase because medication is withheld. Also, risks of toxicity increase when women receive certain new drugs only in the postmarketing phase. Remedies to increase participation of young, nonpregnant women in clinical trials are discussed.
AB - Young women serve less frequently than young men as subjects in premarketing clinical drug trials. Moral, legal, and medical implications of this underrepresentation of women are considered. Risks of medical harm to female patients can increase because medication is withheld. Also, risks of toxicity increase when women receive certain new drugs only in the postmarketing phase. Remedies to increase participation of young, nonpregnant women in clinical trials are discussed.
UR - http://www.scopus.com/inward/record.url?scp=0019409070&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0019409070&partnerID=8YFLogxK
U2 - 10.7326/0003-4819-95-4-495
DO - 10.7326/0003-4819-95-4-495
M3 - Article
C2 - 7283301
AN - SCOPUS:0019409070
VL - 95
SP - 495
EP - 499
JO - [No source information available]
JF - [No source information available]
SN - 0042-1215
IS - 4
ER -