TY - JOUR
T1 - Understanding associative false memories in aging using multivariate analyses
AU - Dennis, Nancy A.
AU - Overman, Amy A.
AU - Carpenter, Catherine M.
AU - Gerver, Courtney R.
N1 - Funding Information:
This work was supported by the NSF [BCS1025709,BCS2000047]; National Institute on Aging [R15AG052903]. We thank Kayla McGraw, M. Andrew Rowley, Joanna Salerno, Harini Babu, and Chloe Hultman for their help with data collection and analyses. We also thank Jordan Chamberlain, Dan Elbich, and Ashley Steinkrauss for analysis support and help with earlier versions of this work. This work was supported by the National Institutes of Health under grant R15AG052903 awarded to A.A.O. and N.A.D. In addition, N.A.D. was also supported in part by National Science Foundation grants BCS1025709 and BCS2000047. Portions of the research in this article used the Color FERET (Facial Recognition Technology) database of facial images collected under the FERET program, sponsored by the Department of Defense Counterdrug Technology Development Program Office.
Funding Information:
We thank Kayla McGraw, M. Andrew Rowley, Joanna Salerno, Harini Babu, and Chloe Hultman for their help with data collection and analyses. We also thank Jordan Chamberlain, Dan Elbich, and Ashley Steinkrauss for analysis support and help with earlier versions of this work. This work was supported by the National Institutes of Health under grant R15AG052903 awarded to A.A.O. and N.A.D. In addition, N.A.D. was also supported in part by National Science Foundation grants BCS1025709 and BCS2000047. Portions of the research in this article used the Color FERET (Facial Recognition Technology) database of facial images collected under the FERET program, sponsored by the Department of Defense Counterdrug Technology Development Program Office.
Publisher Copyright:
© 2022 Informa UK Limited, trading as Taylor & Francis Group.
PY - 2022
Y1 - 2022
N2 - Age-related declines in associative memory are ubiquitous, with decreases in behavioral discriminability largely arising from increases in false memories for recombined lures. Using representational similarity analyses to examine the neural basis of associative false memories in aging, the current study found that neural pattern similarity between Hits and FAs and Hits and CRs differed as a function of age in occipital ROIs, such that older adults exhibited a smaller difference between the two similarity metrics than did younger adults. Additionally, greater Hit-FA representational similarity correlated with increases in associative FAs across several ROIs. Results suggest that while neural representations underlying targets may not differ across ages, greater pattern similarity between the neural representation of targets and lures may reflect reduced distinctiveness of the information encoded in memory, such that old and new items are more difficult to discriminate, leading to more false alarms.
AB - Age-related declines in associative memory are ubiquitous, with decreases in behavioral discriminability largely arising from increases in false memories for recombined lures. Using representational similarity analyses to examine the neural basis of associative false memories in aging, the current study found that neural pattern similarity between Hits and FAs and Hits and CRs differed as a function of age in occipital ROIs, such that older adults exhibited a smaller difference between the two similarity metrics than did younger adults. Additionally, greater Hit-FA representational similarity correlated with increases in associative FAs across several ROIs. Results suggest that while neural representations underlying targets may not differ across ages, greater pattern similarity between the neural representation of targets and lures may reflect reduced distinctiveness of the information encoded in memory, such that old and new items are more difficult to discriminate, leading to more false alarms.
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U2 - 10.1080/13825585.2022.2037500
DO - 10.1080/13825585.2022.2037500
M3 - Article
C2 - 35147489
AN - SCOPUS:85125251472
SN - 1382-5585
VL - 29
SP - 500
EP - 525
JO - Aging, Neuropsychology, and Cognition
JF - Aging, Neuropsychology, and Cognition
IS - 3
ER -
