Understanding Herd Immunity

C. J.E. Metcalf, M. Ferrari, A. L. Graham, B. T. Grenfell

Research output: Contribution to journalComment/debate

31 Scopus citations

Abstract

Individual immunity is a powerful force affecting host health and pathogen evolution. Importantly, the effects of individual immunity also scale up to affect pathogen transmission dynamics and the success of vaccination campaigns for entire host populations. Popu- lation-scale immunity is often termed 'herd immunity'. Here we outline how individual immunity maps to population outcomes and discuss implications for control of infectious diseases. Particu- lar immunological characteristics may be more or less likely to result in a population level signature of herd immunity; we detail this and also discuss other population-level outcomes that might emerge from individual-level immunity.

Original languageEnglish (US)
Pages (from-to)753-755
Number of pages3
JournalTrends in Immunology
Volume36
Issue number12
DOIs
StatePublished - Dec 1 2015

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Immunology

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    Metcalf, C. J. E., Ferrari, M., Graham, A. L., & Grenfell, B. T. (2015). Understanding Herd Immunity. Trends in Immunology, 36(12), 753-755. https://doi.org/10.1016/j.it.2015.10.004