Upg-2: A urinary pepsinogen variant located on chromosome 1 of the mouse

Jacek M. Szymura, Benjamin A. Taylor, Jan Klein

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Acrylamide gel electrophoresis of mouse urine distinguishes two groups of pepsinogens, the fast-migrating group A and the slow-migrating group B. Inbred mouse strains fall into two categories with respect to group B pepsinogens, one expressing a single-banded and the other a double-banded phenotype. This variation is controlled by a single locus, urinary pepsinogen-2 or Upg-2, which has at least two alleles, Upg-2s and Upg-2d. Typing of recombinant inbred strains suggests that the location of the Upg-2 locus is on chromosome 1, in the vicinity of loci coding for other peptidases, namely, Pep-2 and Rnr, and of the Acf-1 locus.

Original languageEnglish (US)
Pages (from-to)1211-1219
Number of pages9
JournalBiochemical Genetics
Volume20
Issue number11-12
DOIs
StatePublished - Dec 1982

All Science Journal Classification (ASJC) codes

  • Ecology, Evolution, Behavior and Systematics
  • Biochemistry
  • Molecular Biology
  • Genetics

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