Use of antithrombotic drugs in the treatment of acute ischemic stroke: A survey of neurologists in practice in the United States

E. E. Marsh, H. P. Adams, J. Biller, P. Wasek, K. Banwart, V. Mitchell, R. Woolson

Research output: Contribution to journalArticlepeer-review

66 Scopus citations

Abstract

Inan attempt to determine the opinions and practices of neurologists regarding the use of antithrombotic drugs in the treatment of acute ischemic stroke, we conducted a survey of 349 randomly selected neurologists from throughout the United States. Responses were received from 247 (71%), and 219 identified themselves as primary or consulting physicians for patients with acute ischemic stroke. During the previous 12 months, these 219 physicians estimated that they had seen a total of 14,636 patients within 24 hours of acute ischemic stroke, and 22% of these patients were treated with heparin. The most frequently reported indications were prevention of recurrent cerebral embolism (82% of physicians) and progressing stroke (70%). Despite the frequent use of heparin, only 6.4% of neurologists felt that it has been shown to be effective, and 16.4% felt that it has been shown to be of no value. The primary concern about the use of heparin was lack of proven efficacy in 48% and safety concerns in 41%. Results of a future trial testing the efficacy of antithrombotic drugs would be useful for most neurologists in their management of patients with acute or progressing ischemic stroke.

Original languageEnglish (US)
Pages (from-to)1631-1634
Number of pages4
JournalNeurology
Volume39
Issue number12
DOIs
StatePublished - Dec 1989

All Science Journal Classification (ASJC) codes

  • Clinical Neurology

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