Use of esterified retinol to trace the degradation of chylomicrons in cholesterol-fed rabbits.

A. Catharine Ross, D. B. Zilversmit

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Moderately hypercholesterolemic rabbits hydrolyzed chylomicron TG at the same rate as normal animals, but were found to accumulate partially degraded intestinal lipoproteins of Sf 100-400 and Sf 20-100. These results support the hypothesis that the hypercholesterolemia induced by cholesterol feeding results at least in part from an inability to clear chylomicron remnants in proportion to the rate of their formation.

Original languageEnglish (US)
Pages (from-to)142-145
Number of pages4
JournalAdvances in Experimental Medicine and Biology
Volume82
StatePublished - 1977

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Chylomicron Remnants
Chylomicrons
Hypercholesterolemia
Vitamin A
Lipoproteins
Animals
Cholesterol
Rabbits
Degradation

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)

Cite this

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abstract = "Moderately hypercholesterolemic rabbits hydrolyzed chylomicron TG at the same rate as normal animals, but were found to accumulate partially degraded intestinal lipoproteins of Sf 100-400 and Sf 20-100. These results support the hypothesis that the hypercholesterolemia induced by cholesterol feeding results at least in part from an inability to clear chylomicron remnants in proportion to the rate of their formation.",
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}

Use of esterified retinol to trace the degradation of chylomicrons in cholesterol-fed rabbits. / Ross, A. Catharine; Zilversmit, D. B.

In: Advances in Experimental Medicine and Biology, Vol. 82, 1977, p. 142-145.

Research output: Contribution to journalArticle

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AU - Ross, A. Catharine

AU - Zilversmit, D. B.

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AB - Moderately hypercholesterolemic rabbits hydrolyzed chylomicron TG at the same rate as normal animals, but were found to accumulate partially degraded intestinal lipoproteins of Sf 100-400 and Sf 20-100. These results support the hypothesis that the hypercholesterolemia induced by cholesterol feeding results at least in part from an inability to clear chylomicron remnants in proportion to the rate of their formation.

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