Use of esterified retinol to trace the degradation of chylomicrons in cholesterol-fed rabbits.

A. C. Ross, D. B. Zilversmit

Research output: Contribution to journalArticlepeer-review

12 Scopus citations

Abstract

Moderately hypercholesterolemic rabbits hydrolyzed chylomicron TG at the same rate as normal animals, but were found to accumulate partially degraded intestinal lipoproteins of Sf 100-400 and Sf 20-100. These results support the hypothesis that the hypercholesterolemia induced by cholesterol feeding results at least in part from an inability to clear chylomicron remnants in proportion to the rate of their formation.

Original languageEnglish (US)
Pages (from-to)142-145
Number of pages4
JournalAdvances in experimental medicine and biology
Volume82
DOIs
StatePublished - 1977

All Science Journal Classification (ASJC) codes

  • Biochemistry, Genetics and Molecular Biology(all)

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