Use of Stang's reagent, PhI(CN)OTf, to promote Pummerer-like oxidative cyclization of 2-(phenylthio)indoles

Ken S. Feldman, Daniela Boneva Vidulova

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Treatment of various 2-(phenylthio)indoles, bearing nucleophilic groups tethered to C(3), with PhI(CN)OTf initiated an oxidative cyclization sequence that afforded 3,3-spirocyclic 2-(phenylthio)indolenines or oxindoles in moderate yield.

Original languageEnglish (US)
Pages (from-to)5035-5037
Number of pages3
JournalTetrahedron Letters
Volume45
Issue number26
DOIs
StatePublished - Jun 21 2004

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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