Using the abbreviated injury severity and glasgow coma scale scores to predict 2-week mortality after traumatic brain injury

Shelly D. Timmons, Tiffany Bee, Sharon Webb, Ramon R. Diaz-Arrastia, Dale Hesdorffer

Research output: Contribution to journalArticle

39 Scopus citations

Abstract

Background: Prediction of outcome after traumatic brain injury (TBI) remains elusive. We tested the use of a single hospital Glasgow Coma Scale (GCS) Score, GCS Motor Score, and the Head component of the Abbreviated Injury Scale (AIS) Score to predict 2-week cumulative mortality in a large cohort of TBI patients admitted to the eight U.S. Level I trauma centers in the TBI Clinical Trials Network. Methods: Data on 2,808 TBI patients were entered into a centralized database. These TBI patients were categorized as severe (GCS score, 3-8), moderate (9-12), or complicated mild (13-15 with positive computed tomography findings). Intubation and chemical paralysis were recorded. The cumulative incidence of mortality in the first 2 weeks after head injury was calculated using Kaplan-Meier survival analysis. Cox proportional hazards regression was used to estimate the magnitude of the risk for 2-week mortality. Results: Two-week cumulative mortality was independently predicted by GCS, GCS Motor Score, and Head AIS. GCS Severity Category and GCS Motor Score were stronger predictors of 2-week mortality than Head AIS. There was also an independent effect of age (<60 vs. ≤60) on mortality after controlling for both GCS and Head AIS Scores. Conclusions: Anatomic and physiologic scales are useful in the prediction of mortality after TBI. We did not demonstrate any added benefit to combining the total GCS or GCS Motor Scores with the Head AIS Score in the short-term prediction of death after TBI.

Original languageEnglish (US)
Pages (from-to)1172-1178
Number of pages7
JournalJournal of Trauma - Injury, Infection and Critical Care
Volume71
Issue number5
DOIs
StatePublished - Nov 1 2011

All Science Journal Classification (ASJC) codes

  • Surgery
  • Critical Care and Intensive Care Medicine

Fingerprint Dive into the research topics of 'Using the abbreviated injury severity and glasgow coma scale scores to predict 2-week mortality after traumatic brain injury'. Together they form a unique fingerprint.

  • Cite this