Utility of Ct values in differentiating COVID-19 reinfection versus prolonged viral shedding in an immunocompromised patient

Katherine Julian, Neal Shah, Rashmi Banjade, Dhirisha Bhatt

Research output: Contribution to journalArticlepeer-review

Abstract

We describe the case of a 26-year-old man who presented to an outside hospital with concerns of blurred vision. He subsequently tested positive for COVID-19 and his lab work suggested acute leukaemia. The patient was admitted to our hospital and completed a course of remdesivir. He eventually tested negative for COVID-19 before initiating chemotherapy. Two days after starting chemotherapy, he developed a neutropenic fever and tested positive for COVID-19. Through this case, we aim to bring attention to patients who recurrently test positive with COVID-19 PCR testing, thereby causing a dilemma of differentiating between reinfections and prolonged shedding of the virus, as well as understand and use cycle threshold values to discern these aetiologies.

Original languageEnglish (US)
Article numbere243692
JournalBMJ case reports
Volume14
Issue number7
DOIs
StatePublished - Jul 27 2021

All Science Journal Classification (ASJC) codes

  • Medicine(all)

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