Utility of echocardiographic radial strain imaging to quantify left ventricular dyssynchrony and predict acute response to cardiac resynchronization therapy

Kaoru Dohi, Matthew S. Suffoletto, David Schwartzman, Leonard Ganz, Michael R. Pinsky, John Gorcsan

Research output: Contribution to journalArticlepeer-review

Abstract

Echocardiographic strain imaging was used to quantify radial mechanical dyssynchrony in 38 patients who underwent cardiac resynchronization therapy. Dyssynchrony, defined as the time difference of peak radial strain in the septum versus the posterior wall, was significantly greater in patients with acute hemodynamic responses, and changes in radial dyssynchrony correlated with changes in stroke volume. A <130-ms difference in septal versus posterior wall peak strain when combined with a favorable left ventricular lead position was strongly predictive of immediate improvement in stroke volume with resynchronization therapy (95% sensitivity, 88% specificity), regardless of electrocardiographic QRS duration.

Original languageEnglish (US)
Pages (from-to)112-116
Number of pages5
JournalAmerican Journal of Cardiology
Volume96
Issue number1
DOIs
StatePublished - Jul 1 2005

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine

Fingerprint Dive into the research topics of 'Utility of echocardiographic radial strain imaging to quantify left ventricular dyssynchrony and predict acute response to cardiac resynchronization therapy'. Together they form a unique fingerprint.

Cite this