Validation study of fractional exhaled nitric oxide measurements using a handheld monitoring device

Michelle Gill, Gavin R. Graff, Alan J. Adler, Raed A. Dweik

Research output: Contribution to journalArticle

34 Scopus citations

Abstract

We tested reproducibility of exhaled nitric oxide (FENO) and inter-operator handling when measured with a handheld device, NIOX MINO®. We enrolled 20 volunteers using a priori goals of acceptable reproducibility to be mean within-subject standard deviation less than 3 parts per billion (ppb) for FENO measurements less than 30 ppb, and mean coefficient of variation less than 10% for FENO measurements more than 30 ppb. Seventeen subjects with measurements less than 30 ppb displayed a mean standard deviation of 1.15, and 3 subjects with FENO more than 30 ppb had a mean coefficient of variation of 2.4%. We conclude that NIOX MINO demonstrates excellent reproducibility for all ranges of FENO.

Original languageEnglish (US)
Pages (from-to)731-734
Number of pages4
JournalJournal of Asthma
Volume43
Issue number10
DOIs
StatePublished - Dec 1 2006

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health
  • Immunology and Allergy
  • Pulmonary and Respiratory Medicine

Fingerprint Dive into the research topics of 'Validation study of fractional exhaled nitric oxide measurements using a handheld monitoring device'. Together they form a unique fingerprint.

  • Cite this