Vector competence of selected North American Anopheles and Culex mosquitoes for Zika virus

Brittany L. Dodson, Sujit Pujhari, Jason L. Rasgon

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Zika virus (ZIKV) is a vector-borne flavivirus that has caused recent outbreaks associated with serious disease in infants and newborns in the Americas. Aedes mosquitoes are the primary vectors for ZIKV, but little is known about the diversity of mosquitoes that can transmit ZIKV in North America. We chose three abundant North American mosquito species (Anopheles freeborni, Anopheles quadrimaculatus, and Culex tarsalis) and one known vector species (Aedes aegypti), fed them blood meals supplemented with a recent outbreak ZIKV strain, and tested bodies, legs, and saliva for infectious ZIKV. ZIKV was able to infect, disseminate, and be transmitted by Aedes aegypti. However, Anopheles freeborni, Anopheles quadrimaculatus, and Culex tarsalis were unable to be infected. We conclude that these species are unlikely to be involved in ZIKV transmission in North America. However, we should continue to examine the ability for other mosquito species to potentially act as ZIKV vectors in North America.

Original languageEnglish (US)
Article numbere4324
JournalPeerJ
Volume2018
Issue number2
DOIs
StatePublished - Jan 1 2018

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Zika virus
vector competence
Culex
Anopheles
Culicidae
Viruses
Mental Competency
Aedes
North America
Anopheles freeborni
Anopheles quadrimaculatus
Culex tarsalis
Aedes aegypti
Disease Outbreaks
Infant, Newborn, Diseases
Flavivirus
Aptitude
Zika Virus
blood meal
virus transmission

All Science Journal Classification (ASJC) codes

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

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abstract = "Zika virus (ZIKV) is a vector-borne flavivirus that has caused recent outbreaks associated with serious disease in infants and newborns in the Americas. Aedes mosquitoes are the primary vectors for ZIKV, but little is known about the diversity of mosquitoes that can transmit ZIKV in North America. We chose three abundant North American mosquito species (Anopheles freeborni, Anopheles quadrimaculatus, and Culex tarsalis) and one known vector species (Aedes aegypti), fed them blood meals supplemented with a recent outbreak ZIKV strain, and tested bodies, legs, and saliva for infectious ZIKV. ZIKV was able to infect, disseminate, and be transmitted by Aedes aegypti. However, Anopheles freeborni, Anopheles quadrimaculatus, and Culex tarsalis were unable to be infected. We conclude that these species are unlikely to be involved in ZIKV transmission in North America. However, we should continue to examine the ability for other mosquito species to potentially act as ZIKV vectors in North America.",
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Vector competence of selected North American Anopheles and Culex mosquitoes for Zika virus. / Dodson, Brittany L.; Pujhari, Sujit; Rasgon, Jason L.

In: PeerJ, Vol. 2018, No. 2, e4324, 01.01.2018.

Research output: Contribution to journalArticle

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