Vertebral disc space infection and osteomyelitis due to candida albicans in a patient with acute myelomonocytic leukemia

Bahu S. Shaikh, Peter C. Appelbaum, Robert Aber

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

A 67‐year old man with acute myelomonocytic leukemia had Candida albicans fungemia during induction chemotherapy. Bilateral pulmonary infiltrates and hepatic granulomata containing yeast forms and septate hyphae developed, but cultures of the hepatic tissue failed to grow a fungus. Although his pulmonary and liver disease improved following appropriate therapy, vertebral osteomyelitis due to Candida albicans developed approximately 12–15 weeks after the original fungemia. The fungal osteomyelitis was successfully treated with amphotericin B and 5‐fluorocytosine. This case illustrates the need for early diagnosis and aggressive treatment of fungal infections in patients with leukemia.

Original languageEnglish (US)
Pages (from-to)1025-1028
Number of pages4
JournalCancer
Volume45
Issue number5
DOIs
StatePublished - Jan 1 1980

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Leukemia, Myelomonocytic, Acute
Fungemia
Osteomyelitis
Candida albicans
Induction Chemotherapy
Hyphae
Mycoses
Liver
Amphotericin B
Infection
Granuloma
Lung Diseases
Liver Diseases
Early Diagnosis
Leukemia
Fungi
Yeasts
Lung
Therapeutics

All Science Journal Classification (ASJC) codes

  • Oncology
  • Cancer Research

Cite this

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Vertebral disc space infection and osteomyelitis due to candida albicans in a patient with acute myelomonocytic leukemia. / Shaikh, Bahu S.; Appelbaum, Peter C.; Aber, Robert.

In: Cancer, Vol. 45, No. 5, 01.01.1980, p. 1025-1028.

Research output: Contribution to journalArticle

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