Abstract
Safety and antigenicity of a purified preparation of Salmonella typhosa Vi antigen was evaluated in human volunteers. Dosages of Vi antigen at 25, 50, and 100 μg were less toxic than U.S. standard typhoid vaccine (lot 6A) containing 5 x 10 8 bacteria oer dosage. Vi antigen in comparison with the standard typhoid vaccine induced higher hemagglutinating antibody but lower bactericidal antibody responses.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1290-1294 |
| Number of pages | 5 |
| Journal | Infection and Immunity |
| Volume | 12 |
| Issue number | 6 |
| State | Published - Dec 1 1975 |
Fingerprint
All Science Journal Classification (ASJC) codes
- Parasitology
- Microbiology
- Immunology
- Infectious Diseases
Cite this
}
Vi antigen from Salmonella typhosa and immunity against typhoid fever. II. Safety and antigenicity in humans. / Levin, D. M.; Wong, K. H.; Reynolds, H. Y.; Sutton, A.; Northrup, R. S.
In: Infection and Immunity, Vol. 12, No. 6, 01.12.1975, p. 1290-1294.Research output: Contribution to journal › Article
TY - JOUR
T1 - Vi antigen from Salmonella typhosa and immunity against typhoid fever. II. Safety and antigenicity in humans
AU - Levin, D. M.
AU - Wong, K. H.
AU - Reynolds, H. Y.
AU - Sutton, A.
AU - Northrup, R. S.
PY - 1975/12/1
Y1 - 1975/12/1
N2 - Safety and antigenicity of a purified preparation of Salmonella typhosa Vi antigen was evaluated in human volunteers. Dosages of Vi antigen at 25, 50, and 100 μg were less toxic than U.S. standard typhoid vaccine (lot 6A) containing 5 x 10 8 bacteria oer dosage. Vi antigen in comparison with the standard typhoid vaccine induced higher hemagglutinating antibody but lower bactericidal antibody responses.
AB - Safety and antigenicity of a purified preparation of Salmonella typhosa Vi antigen was evaluated in human volunteers. Dosages of Vi antigen at 25, 50, and 100 μg were less toxic than U.S. standard typhoid vaccine (lot 6A) containing 5 x 10 8 bacteria oer dosage. Vi antigen in comparison with the standard typhoid vaccine induced higher hemagglutinating antibody but lower bactericidal antibody responses.
UR - http://www.scopus.com/inward/record.url?scp=0016761730&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0016761730&partnerID=8YFLogxK
M3 - Article
VL - 12
SP - 1290
EP - 1294
JO - Infection and Immunity
JF - Infection and Immunity
SN - 0019-9567
IS - 6
ER -