Viral genome replication

Craig Eugene Cameron, Kevin D. Raney, Matthias Götte

Research output: Book/ReportBook

4 Citations (Scopus)

Abstract

Provides the first comprehensive review of viral genome replication strategies, emphasizing not only pathways and regulation but also the structure-function, mechanism, and inhibition of proteins and enzymes required for this process Currently, there is no single source that permits comparison of the factors, elements, enzymes and/or mechanisms employed by different classes of viruses for genome replication. As a result, we (and our students) often restrict our focus to our particular system, missing out on the opportunity to define unifying themes in viral genome replication or benefit from the advances in other systems. For example, extraordinary biological and experimental paradigms that have been established over the past five years for the DNA replication systems of bacteriophage T4 and T7 will likely be of great value to anyone interested in studying a replisome from any virus. These studies could easily go unnoticed by animal RNA and DNA virologists. It is our hope that this monograph will cross-fertilize and invigorate the field, as well as encourage students into this area of research.

Original languageEnglish (US)
PublisherSpringer US
Number of pages636
ISBN (Electronic)9780387894560
ISBN (Print)9780387894256
DOIs
StatePublished - Jan 1 2009

Fingerprint

Viral Genome
Students
Bacteriophage T7
Bacteriophage T4
Enzymes
Virus Replication
DNA Replication
Genome
RNA
Viruses
DNA
Research
Proteins

All Science Journal Classification (ASJC) codes

  • Medicine(all)
  • Immunology and Microbiology(all)

Cite this

Cameron, C. E., Raney, K. D., & Götte, M. (2009). Viral genome replication. Springer US. https://doi.org/10.1007/b135974
Cameron, Craig Eugene ; Raney, Kevin D. ; Götte, Matthias. / Viral genome replication. Springer US, 2009. 636 p.
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Cameron, CE, Raney, KD & Götte, M 2009, Viral genome replication. Springer US. https://doi.org/10.1007/b135974

Viral genome replication. / Cameron, Craig Eugene; Raney, Kevin D.; Götte, Matthias.

Springer US, 2009. 636 p.

Research output: Book/ReportBook

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Cameron CE, Raney KD, Götte M. Viral genome replication. Springer US, 2009. 636 p. https://doi.org/10.1007/b135974