Visceral to subcutaneous fat ratio predicts acuity of diverticulitis

Salvatore Docimo, Young Lee, Prav Chatani, Ann Rogers, Frank Lacqua

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Introduction: There is an association between obesity and more complicated diverticular disease. We hypothesize that this link may be due to an increased level of visceral fat rather than an elevated body mass index alone. Adipose tissue secretes inflammatory cytokines, and chronic inflammation may account for the link between obesity and a more severe presentation of diverticular disease. We have applied a quantitative measure of visceral fat content in a series of patients admitted with diverticulitis, comparing those who required emergent versus elective surgical procedures for diverticulitis. Methods: We performed a retrospective review of all adult patients who underwent emergent or elective surgery at our institution for diverticulitis from 2010 to 2014. Data were collected on demographics, comorbidities, operative findings, complications, and length of stay. Radiologic measurements of adiposity were obtained from preoperative CT scans. Visceral fat areas and subcutaneous fat areas were measured, and the V/S ratio was calculated. Results: Thirty-four patients underwent emergent and 32 patients underwent elective surgery. The mean age was 66.3 years for the emergent and 57.11 for the elective group (p = 0.04178). The perinephric, visceral, subcutaneous fat, and V/S ratio for the emergent group were 1.71, 185.22, 338.22, and 0.56 and were 1.11, 127.18, 295.28, and 0.46 for the elective group. The difference between the V/S ratio for each group was significant (p = 0.0238). The emergent group had an average LOS of 16.11 days compared to 5.15 for the elective group (p = <0.00001). The complication rate was significantly higher (p = 0.024) in the emergent group (n = 12, 35.2 %) compared to the elective group (n = 4, 12.5 %). Conclusion: Our study demonstrates a clinically significant link between visceral fat and severity of presentation of diverticulitis. Patients with higher V/S fat ratios were more likely to require emergency surgery and have more complications and a longer LOS.

Original languageEnglish (US)
Pages (from-to)2808-2812
Number of pages5
JournalSurgical endoscopy
Volume31
Issue number7
DOIs
StatePublished - Jul 1 2017

Fingerprint

Diverticulitis
Intra-Abdominal Fat
Subcutaneous Fat
Obesity
Elective Surgical Procedures
Adiposity
Adipose Tissue
Comorbidity
Length of Stay
Body Mass Index
Emergencies
Fats
Demography
Cytokines
Inflammation

All Science Journal Classification (ASJC) codes

  • Surgery

Cite this

Docimo, Salvatore ; Lee, Young ; Chatani, Prav ; Rogers, Ann ; Lacqua, Frank. / Visceral to subcutaneous fat ratio predicts acuity of diverticulitis. In: Surgical endoscopy. 2017 ; Vol. 31, No. 7. pp. 2808-2812.
@article{a2ea4d9396224ac196d45aeed77abe0a,
title = "Visceral to subcutaneous fat ratio predicts acuity of diverticulitis",
abstract = "Introduction: There is an association between obesity and more complicated diverticular disease. We hypothesize that this link may be due to an increased level of visceral fat rather than an elevated body mass index alone. Adipose tissue secretes inflammatory cytokines, and chronic inflammation may account for the link between obesity and a more severe presentation of diverticular disease. We have applied a quantitative measure of visceral fat content in a series of patients admitted with diverticulitis, comparing those who required emergent versus elective surgical procedures for diverticulitis. Methods: We performed a retrospective review of all adult patients who underwent emergent or elective surgery at our institution for diverticulitis from 2010 to 2014. Data were collected on demographics, comorbidities, operative findings, complications, and length of stay. Radiologic measurements of adiposity were obtained from preoperative CT scans. Visceral fat areas and subcutaneous fat areas were measured, and the V/S ratio was calculated. Results: Thirty-four patients underwent emergent and 32 patients underwent elective surgery. The mean age was 66.3 years for the emergent and 57.11 for the elective group (p = 0.04178). The perinephric, visceral, subcutaneous fat, and V/S ratio for the emergent group were 1.71, 185.22, 338.22, and 0.56 and were 1.11, 127.18, 295.28, and 0.46 for the elective group. The difference between the V/S ratio for each group was significant (p = 0.0238). The emergent group had an average LOS of 16.11 days compared to 5.15 for the elective group (p = <0.00001). The complication rate was significantly higher (p = 0.024) in the emergent group (n = 12, 35.2 {\%}) compared to the elective group (n = 4, 12.5 {\%}). Conclusion: Our study demonstrates a clinically significant link between visceral fat and severity of presentation of diverticulitis. Patients with higher V/S fat ratios were more likely to require emergency surgery and have more complications and a longer LOS.",
author = "Salvatore Docimo and Young Lee and Prav Chatani and Ann Rogers and Frank Lacqua",
year = "2017",
month = "7",
day = "1",
doi = "10.1007/s00464-016-5290-2",
language = "English (US)",
volume = "31",
pages = "2808--2812",
journal = "Surgical Endoscopy",
issn = "0930-2794",
publisher = "Springer New York",
number = "7",

}

Visceral to subcutaneous fat ratio predicts acuity of diverticulitis. / Docimo, Salvatore; Lee, Young; Chatani, Prav; Rogers, Ann; Lacqua, Frank.

In: Surgical endoscopy, Vol. 31, No. 7, 01.07.2017, p. 2808-2812.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Visceral to subcutaneous fat ratio predicts acuity of diverticulitis

AU - Docimo, Salvatore

AU - Lee, Young

AU - Chatani, Prav

AU - Rogers, Ann

AU - Lacqua, Frank

PY - 2017/7/1

Y1 - 2017/7/1

N2 - Introduction: There is an association between obesity and more complicated diverticular disease. We hypothesize that this link may be due to an increased level of visceral fat rather than an elevated body mass index alone. Adipose tissue secretes inflammatory cytokines, and chronic inflammation may account for the link between obesity and a more severe presentation of diverticular disease. We have applied a quantitative measure of visceral fat content in a series of patients admitted with diverticulitis, comparing those who required emergent versus elective surgical procedures for diverticulitis. Methods: We performed a retrospective review of all adult patients who underwent emergent or elective surgery at our institution for diverticulitis from 2010 to 2014. Data were collected on demographics, comorbidities, operative findings, complications, and length of stay. Radiologic measurements of adiposity were obtained from preoperative CT scans. Visceral fat areas and subcutaneous fat areas were measured, and the V/S ratio was calculated. Results: Thirty-four patients underwent emergent and 32 patients underwent elective surgery. The mean age was 66.3 years for the emergent and 57.11 for the elective group (p = 0.04178). The perinephric, visceral, subcutaneous fat, and V/S ratio for the emergent group were 1.71, 185.22, 338.22, and 0.56 and were 1.11, 127.18, 295.28, and 0.46 for the elective group. The difference between the V/S ratio for each group was significant (p = 0.0238). The emergent group had an average LOS of 16.11 days compared to 5.15 for the elective group (p = <0.00001). The complication rate was significantly higher (p = 0.024) in the emergent group (n = 12, 35.2 %) compared to the elective group (n = 4, 12.5 %). Conclusion: Our study demonstrates a clinically significant link between visceral fat and severity of presentation of diverticulitis. Patients with higher V/S fat ratios were more likely to require emergency surgery and have more complications and a longer LOS.

AB - Introduction: There is an association between obesity and more complicated diverticular disease. We hypothesize that this link may be due to an increased level of visceral fat rather than an elevated body mass index alone. Adipose tissue secretes inflammatory cytokines, and chronic inflammation may account for the link between obesity and a more severe presentation of diverticular disease. We have applied a quantitative measure of visceral fat content in a series of patients admitted with diverticulitis, comparing those who required emergent versus elective surgical procedures for diverticulitis. Methods: We performed a retrospective review of all adult patients who underwent emergent or elective surgery at our institution for diverticulitis from 2010 to 2014. Data were collected on demographics, comorbidities, operative findings, complications, and length of stay. Radiologic measurements of adiposity were obtained from preoperative CT scans. Visceral fat areas and subcutaneous fat areas were measured, and the V/S ratio was calculated. Results: Thirty-four patients underwent emergent and 32 patients underwent elective surgery. The mean age was 66.3 years for the emergent and 57.11 for the elective group (p = 0.04178). The perinephric, visceral, subcutaneous fat, and V/S ratio for the emergent group were 1.71, 185.22, 338.22, and 0.56 and were 1.11, 127.18, 295.28, and 0.46 for the elective group. The difference between the V/S ratio for each group was significant (p = 0.0238). The emergent group had an average LOS of 16.11 days compared to 5.15 for the elective group (p = <0.00001). The complication rate was significantly higher (p = 0.024) in the emergent group (n = 12, 35.2 %) compared to the elective group (n = 4, 12.5 %). Conclusion: Our study demonstrates a clinically significant link between visceral fat and severity of presentation of diverticulitis. Patients with higher V/S fat ratios were more likely to require emergency surgery and have more complications and a longer LOS.

UR - http://www.scopus.com/inward/record.url?scp=84992179558&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84992179558&partnerID=8YFLogxK

U2 - 10.1007/s00464-016-5290-2

DO - 10.1007/s00464-016-5290-2

M3 - Article

C2 - 27778168

AN - SCOPUS:84992179558

VL - 31

SP - 2808

EP - 2812

JO - Surgical Endoscopy

JF - Surgical Endoscopy

SN - 0930-2794

IS - 7

ER -