Vitamin A as a hormone: Recent advances in understanding the actions of retinol, retinoic acid, and beta carotene

A. Catharine Ross, Maureen E. Ternus

Research output: Contribution to journalReview article

33 Citations (Scopus)

Abstract

Within the past few years, much has been learned about the metabolism and actions of vitamin A and the carotenoids. This article reviews the biochemical and cellular events in retinoid metabolism that lead to production of retinoic acid, an active metabolite of vitamin A. Retinoic acid functions in a hormonelike manner to regulate the expression of a number of genes. Beta carotene is now under study as an anticancer agent and for its possible beneficial effects in a number of chronic diseases. Current recommendations for carotene intake exceed the usual daily intake nearly fourfold.

Original languageEnglish (US)
Pages (from-to)1285-1290
Number of pages6
JournalJournal of the American Dietetic Association
Volume93
Issue number11
DOIs
StatePublished - Jan 1 1993

Fingerprint

retinoic acid
beta Carotene
Tretinoin
Vitamin A
vitamin A
beta-carotene
hormones
Hormones
Carotenoids
metabolism
retinoids
antineoplastic agents
carotenes
chronic diseases
carotenoids
Retinoids
metabolites
Antineoplastic Agents
Chronic Disease
genes

All Science Journal Classification (ASJC) codes

  • Food Science
  • Nutrition and Dietetics

Cite this

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abstract = "Within the past few years, much has been learned about the metabolism and actions of vitamin A and the carotenoids. This article reviews the biochemical and cellular events in retinoid metabolism that lead to production of retinoic acid, an active metabolite of vitamin A. Retinoic acid functions in a hormonelike manner to regulate the expression of a number of genes. Beta carotene is now under study as an anticancer agent and for its possible beneficial effects in a number of chronic diseases. Current recommendations for carotene intake exceed the usual daily intake nearly fourfold.",
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Vitamin A as a hormone : Recent advances in understanding the actions of retinol, retinoic acid, and beta carotene. / Ross, A. Catharine; Ternus, Maureen E.

In: Journal of the American Dietetic Association, Vol. 93, No. 11, 01.01.1993, p. 1285-1290.

Research output: Contribution to journalReview article

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