Well-differentiated serous ovarian carcinoma presenting as a breast mass: A case report and flow cytometric dna study

Elizabeth E. Frauenhoffer, Jae Y. Ro, Elvio G. Silva, Adel El-Naggar

Research output: Contribution to journalArticle

11 Scopus citations

Abstract

Ovarian carcinoma metastatic to the breast is uncommon. We report a rare occurrence of ovarian carcinoma that initially presented as a breast mass. Complete examination revealed bilateral ovarian tumors with widespread peritoneal and abdominal disease. One of the ovarian tumors was a papillary serous tumor of low malignant potential, and the other was a well-differentiated papillary serous carcinoma. Although the neoplasm within the breast resembled serous ovarian carcinoma with psammoma bodies, the initial presentation and the presence of an apparent intraductal component created a potential for its misdiagnosis as a primary breast carcinoma. Using DNA flow cytometry, we demonstrated the relationship between the breast, lymph node, and peritoneal metastases and the serous carcinoma, thereby supporting the histologic diagnoses.

Original languageEnglish (US)
Pages (from-to)79-87
Number of pages9
JournalInternational Journal of Gynecological Pathology
Volume10
Issue number1
DOIs
StatePublished - Jan 1991

All Science Journal Classification (ASJC) codes

  • Pathology and Forensic Medicine
  • Obstetrics and Gynecology

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