What can genes tell us about the relationship between education and health?

Jason D. Boardman, Benjamin W. Domingue, Jonathan Kyle Daw

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

We use genome wide data from respondents of the Health and Retirement Study (HRS) to evaluate the possibility that common genetic influences are associated with education and three health outcomes: depression, self-rated health, and body mass index. We use a total of 1.7 million single nucleotide polymorphisms obtained from the Illumina HumanOmni2.5-4v1 chip from 4233 non-Hispanic white respondents to characterize genetic similarities among unrelated persons in the HRS. We then used the Genome Wide Complex Trait Analysis (GCTA) toolkit, to estimate univariate and bivariate heritability. We provide evidence that education (h2=0.33), BMI (h2=0.43), depression (h2=0.19), and self-rated health (h2=0.18) are all moderately heritable phenotypes. We also provide evidence that some of the correlation between depression and education as well as self-rated health and education is due to common genetic factors associated with one or both traits. We find no evidence that the correlation between education and BMI is influenced by common genetic factors.

Original languageEnglish (US)
Pages (from-to)171-180
Number of pages10
JournalSocial Science and Medicine
Volume127
DOIs
StatePublished - Feb 1 2015

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Health Education
Retirement
Health
health
Education
Genes
education
heredity
Genome
retirement
Single Nucleotide Polymorphism
evidence
Body Mass Index
Phenotype
Gene
human being
Surveys and Questionnaires

All Science Journal Classification (ASJC) codes

  • Health(social science)
  • History and Philosophy of Science

Cite this

Boardman, Jason D. ; Domingue, Benjamin W. ; Daw, Jonathan Kyle. / What can genes tell us about the relationship between education and health?. In: Social Science and Medicine. 2015 ; Vol. 127. pp. 171-180.
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What can genes tell us about the relationship between education and health? / Boardman, Jason D.; Domingue, Benjamin W.; Daw, Jonathan Kyle.

In: Social Science and Medicine, Vol. 127, 01.02.2015, p. 171-180.

Research output: Contribution to journalArticle

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