Whole-cell biocatalysis in biphasic media for oxidation of naphthalene

S. V.B. Janardhan Garikipati, Tonya L. Peeples

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Biocatalysis involves the use of enzymes to perform stereo- and enatio-specific reactions producing valuable products in an environmentally benign way. However, the hydrophobic nature of most of the substrates affects the productivity due to poor solubility in aqueous solutions and high toxicity to cells expressing the biocatalyst. These drawbacks can be eliminated by using biphasic media, where a second phase of organic solvent serves as a reservoir of substrate and helps in extracting the products in-situ. The use of biocatalysis in biphasic media is applied to oxidation of napthalane to produce either 1-naphthol or 1,2-naphthalene dihydrodiol.

Original languageEnglish (US)
Title of host publicationAmerican Chemical Society - 235th National Meeting, Abstracts of Scientific Papers
Publication statusPublished - Dec 1 2008
Event235th National Meeting of the American Chemical Society, ACS 2008 - New Orleans, LA, United States
Duration: Apr 6 2008Apr 10 2008

Publication series

NameACS National Meeting Book of Abstracts
ISSN (Print)0065-7727

Other

Other235th National Meeting of the American Chemical Society, ACS 2008
CountryUnited States
CityNew Orleans, LA
Period4/6/084/10/08

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All Science Journal Classification (ASJC) codes

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Janardhan Garikipati, S. V. B., & Peeples, T. L. (2008). Whole-cell biocatalysis in biphasic media for oxidation of naphthalene. In American Chemical Society - 235th National Meeting, Abstracts of Scientific Papers (ACS National Meeting Book of Abstracts).