Whole-cell biocatalysis in biphasic media for oxidation of naphthalene

S. V.B. Janardhan Garikipati, Tonya Peeples

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Biocatalysis involves the use of enzymes to perform stereo- and enatio-specific reactions producing valuable products in an environmentally benign way. However, the hydrophobic nature of most of the substrates affects the productivity due to poor solubility in aqueous solutions and high toxicity to cells expressing the biocatalyst. These drawbacks can be eliminated by using biphasic media, where a second phase of organic solvent serves as a reservoir of substrate and helps in extracting the products in-situ. Oxidation of napthalane to produce either 1-naphthol or 1,2-naphthalene dihydrodiol was studied using biocatalysis in biphasic media. This is an abstract of a paper presented at the AIChE Spring National Meeting (New Orleans, LA 4/6-10/2008).

Original languageEnglish (US)
Title of host publication2008 AIChE Spring National Meeting, Conference Proceedings
Publication statusPublished - Dec 23 2008
Event2008 AIChE Spring National Meeting, Conference - New Orleans, LA, United States
Duration: Apr 6 2008Apr 10 2008

Publication series

Name2008 AIChE Spring National Meeting, Conference Proceedings

Other

Other2008 AIChE Spring National Meeting, Conference
CountryUnited States
CityNew Orleans, LA
Period4/6/084/10/08

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All Science Journal Classification (ASJC) codes

  • Biotechnology
  • Chemical Engineering(all)
  • Bioengineering
  • Safety, Risk, Reliability and Quality

Cite this

Janardhan Garikipati, S. V. B., & Peeples, T. (2008). Whole-cell biocatalysis in biphasic media for oxidation of naphthalene. In 2008 AIChE Spring National Meeting, Conference Proceedings (2008 AIChE Spring National Meeting, Conference Proceedings).