Wolbachia pipientis: An expanding bag of tricks to explore for disease control

Peter E. Cook, Elizabeth A. McGraw

Research output: Contribution to journalShort survey

32 Scopus citations


Wolbachia pipientis are maternally inherited, endosymbiotic bacteria that are widespread among insects. Two recent studies have demonstrated that Wolbachia inhibits the ability of medically significant pathogens, including filarial nematodes, dengue virus and Plasmodium to form infections in the mosquito vector, Aedes aegypti. We highlight the added value of these traits for Wolbachia based biocontrol strategies and evaluate the evidence for the idea that the insect immune response is responsible for the pathogen inhibition.

Original languageEnglish (US)
Pages (from-to)373-375
Number of pages3
JournalTrends in Parasitology
Issue number8
StatePublished - Aug 1 2010


All Science Journal Classification (ASJC) codes

  • Parasitology
  • Infectious Diseases

Cite this