Yarn Reinforced Gelatin Hydrogel As A New Scaffold For Tissue Engineering

Elham Rahimtoroghi, Mehran Kasra, Daniel Hayes

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We fabricated yarn reinforced hydrogel using electrospinning technique. The yarns were characterized by scanning electron microscopy (SEM). We then performed cell studies including measurements of cell viability and proliferation on the yarn reinforced hydrogel, using human adipose derived stromal/stem cells (hADSCs). hADSCs responses on the yarn reinforced hydrogel exhibited suitable cell viability and proliferation for tissue engineering applications. We also investigated the effect of yarns on the cell orientation using F-Actin staining. The results of F-Actin staining showed that the cells oriented along the yarn direction. This study introduces the yarn reinforced hydrogel as a novel scaffold with the potential to use in fibrous tissue engineering applications, such as regeneration of the annulus of the intervertebral disc.

Original languageEnglish (US)
Title of host publication2019 26th National and 4th International Iranian Conference on Biomedical Engineering, ICBME 2019
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages66-69
Number of pages4
ISBN (Electronic)9781728156637
DOIs
StatePublished - Nov 2019
Event26th National and 4th International Iranian Conference on Biomedical Engineering, ICBME 2019 - Tehran, Iran, Islamic Republic of
Duration: Nov 27 2019Nov 28 2019

Publication series

Name2019 26th National and 4th International Iranian Conference on Biomedical Engineering, ICBME 2019

Conference

Conference26th National and 4th International Iranian Conference on Biomedical Engineering, ICBME 2019
CountryIran, Islamic Republic of
CityTehran
Period11/27/1911/28/19

All Science Journal Classification (ASJC) codes

  • Computer Science Applications
  • Biomedical Engineering
  • Modeling and Simulation

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