The site-specific recombination system (FLP) encoded by the yeast plasmid 2-μm circle can also act in yeast on the inverted repeats of the bacterial transposon Tn5. The efficiency of this recombination is dependent on the location of Tn5 within the 2-μm circle genome but can be as high as that observed for 2-μm circle itself. Comparison of the DNA sequences between the Tn5 repeat and the 2-μm circle recombination region reveals certain strikingly similar structural features that might be important in the recombination reaction.
|Original language||English (US)|
|Number of pages||5|
|Journal||Proceedings of the National Academy of Sciences of the United States of America|
|Issue number||23 I|
|State||Published - 1983|
All Science Journal Classification (ASJC) codes