Yeast plasmide 2-μm circle promotes recombination within bacterial transposon Tn5

M. Jayaram, J. R. Broach

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

The site-specific recombination system (FLP) encoded by the yeast plasmid 2-μm circle can also act in yeast on the inverted repeats of the bacterial transposon Tn5. The efficiency of this recombination is dependent on the location of Tn5 within the 2-μm circle genome but can be as high as that observed for 2-μm circle itself. Comparison of the DNA sequences between the Tn5 repeat and the 2-μm circle recombination region reveals certain strikingly similar structural features that might be important in the recombination reaction.

Original languageEnglish (US)
Pages (from-to)7264-7268
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Volume80
Issue number23 I
DOIs
StatePublished - Jan 1 1983

All Science Journal Classification (ASJC) codes

  • General

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